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SKIN ABSORPTION -please read

#1

SKIN ABSORPTION -please read
February 19 2007 at 4:13 PM gingerD (Login gingerD)
SENIOR MEMBER

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Iv been reaserching and would like to share a few things iv found out:looking into the 2 sides of what the skin will absorbe (in no paticular order)-Please note this is not My opinion merly what i have found on different websites with links thankyou.+ please feel free to add your findings

Absorption is a route by which substances can enter the body through the skin. Along with inhalation, ingestion and injection, dermal absorption is a route of exposure for toxic substances and route of administration for medication. Absorption of substances through the skin depends on a number of factors, the most important of which are concentration, duration of contact, solubility, physical condition of the skin and part of the body exposed. Certain substances called carriers can be used to greatly increase the amount of another substances that is able to penetrate the skin. Dimethyl sulfoxide (DMSO) is a carrier that is frequently used to transport medication through the skin. This allows treatment to be localized, unlike with ingestion.
http://en.wikipedia.org/wiki/Absorption_%28skin%29

Absorption Base
An absorption base is used to enable beneficial herbs and ingredients, collagen and vitamins to be absorbed into the surface of the skin. An absorption base allows the active ingredients of a product to penetrate into the skin. Essential oils are an absorption base that can be a mixture of alcohols, acids, oxides, lanolin, esters, sulfur compounds, ketones, ethers, ketones or aldehydes. A good absorption base is fatty acids vitamins and it also moisturizes the skin.OTHER GOOD INFO HERE
http://www.vegetarian-restaurants.net/Ad...smetic.htm

Essential Oils Penetrate
The penetrating characteristic of essential oils greatly enhances their ability to be effective. Essential oils will penetrate into the body when applied to the skin. Placed on the foot they will be distributed to every cell in the body in 21 minutes. They will even penetrate a finger or toe nail to treat fungus underneath.
Essential oils last 20 minutes in the body
Oils are a precursor to set up stage for action and a catalyst to do the work (the bloodstream). Oils go where the need is present and are activated in that area. Testing on thyroid, heart and pancreas showed that the oils reached these organs in 3 seconds. When layered, one oil applied over another, it is faster. The body absorbs the oils fasted by breathing and second fastest by applying to the feet or ears. Essential Oils also cross the blood brain barrier. They piggy-back the energy waves to get into the cells.
http://www.therapure.com/yleo/eowhatr.htm

Compared to other body structures, the skin is unique in being perpetually exposed to the environment.
The rate of dermal absorption of a substance is proportional to both the concentration of the substance and the surface area over which it is applied. The wider the contact area and the more concentrated the substance, the greater will be the absorption.
The thickness of the skin, especially the stratum corneum, also determines the degree to which substances are absorbed. there is much more:
:http://www.cape.ca/children/derm2.html

Some of the aromatic 'essential' oils used in aromatherapy do have well-documented therapeutic actions. However, many of the oils for which aromatherapists claim physiological medical activity, in fact possess no recorded historical medicinal actions
Most aromatherapists claim explicit physical effects after massaging with oils, for example: "Fennel is diuretic," "Geranium regulates the hormonal system," "Grapefruit is good for cellulite." However, none of these effects have been proven when these oils are applied to the skin during massage.
One example of the misleading hype is found with Fennel oil. It is well known for producing an increase in urine output when it is taken as a medicine. However, when the volume of fennel oil used in the average massage is applied, it is doubtful that enough can be absorbed through the skin to elicit any such diuretic action. If very large amounts are used on the skin, or it is occluded - such as with compresses - or the essential oil is used in hot humid environments, then I am prepared to accept some oil may get into the subcutaneous tissues.-PLEASE READ THIS ENTIRE ARTICLE VERY INTERSTING:
/www.aromamedical.com/articles/skinabso.html

Skin absorption studies at the University of Michigan demonstrated that jojoba is quickly absorbed into the skin, which is apparently via the transappendegeal mechanism and occurs through the pores and hair follicles – but because it is so rapidly absorbed, the pores and hair follicles remain open and thus maintain their proper functioning ability.
http://www.ageless.co.za/herb-jojoba.htm#Properties

YOUR SKIN ABSORBS UP TO 60% OF WHATEVER IS APPLIED - INCLUDING TOXIN
http://www.newforestsoaps.co.uk/yourskin.htm

Human skin will not absorb most common waters because of incorrect application and an incompatible pH balance.
http://www.naturesmist.com/skinfunc.html

The skin can absorb chemicals, not just nicotine from patches, but harmful toxins and carcinogens, and yet these can be found in many personal care products.
http://www.bodyandhaircare.co.uk/skincarepage.htm

For example, mineral oil is never used in aromatherapy not only because it is not a natural product but because itmay prevent the absorption of essential oil into the skin. Aromatherapy carrier oils on the other hand function specifically to help the skin absorb essential oil.
http://www.aromafacts.com/aromatherapy-c...-oils.html

Dear Dr. Gott: Does the skin absorb all the bath oils and lip creams that we apply? I use so much lotion and cocoa butter on my hands and feet in the winter that I am concerned about the cholesterol and triglyceride fats that may be entering my body.
Dear Reader: Under ordinary circumstances, the substances in topical products are not absorbed through the skin into the body, although they are absorbed into the skin itself.
http://www.spokesmanreview.com/pf.asp?da...D=s1518870




Author Reply
gingerD
(Login gingerD)
SENIOR MEMBER Re: SKIN ABSORPTION -please read February 19 2007, 4:39 PM


And when searching kept stumbling upon this site;could help?

http://www.intota.com/multisearch.asp?st...absorption
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#2

Skin absorption
August 3 2007 at 7:46 AM Moon (Login -Moon-)
SENIOR MEMBER

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There has been much discussion about transdermal appliaction of all NBE related substances, so I will make the summary of the theory here:

1. Only small and lipid soluable molecules can penetrate the skin. This includes some vitamins and some hormones, but not proteins (including collagen).

2. Phytoestrogens from creams, tinctures and extracts used in NBE are absorbed, but they bypass the liver and don't undergo processing there. This may make the compound more effective, because it is retaind in the body for a loner time (liver degrades and eliminates compounds from the body). But the liver also activates some compounds that enter the body in an inactive form. In this case transdermal application is less effective.

3. Applying large molecules (such as proteins) only resuls in creating a water impermeable layer on the skin causing it to retain moisture.

Articles for further reading:
http://www.abc.net.au/cgi-bin/common/pri...efault.htm
http://molinterv.aspetjournals.org/cgi/c...ll/4/6/308






Author Reply
Moon
(Login -Moon-)
SENIOR MEMBER Re: Skin absorption June 4 2008, 9:29 AM


In the frame of the heated cocoa butter debate, there has been a lot of dispute of whether or not FATS penetrate the skin. Here are my findings:
The previous sources inform me that molecules with the molecular weight up to about 500 Da (daltons) can pass the skin. I calculated the molecular weight of this fat molecule:
http://biology.clc.uc.edu/graphics/bio104/fat.jpg
It's 552 Da. This is a very small fat molecule - the fatty acid chains are only 10 carbon atoms long. Usually they are 12 to 16, often 18 and 22. So it seems that fats do not penetrate the skin.
However, fatty acids do, and this is used in cosmetic and other industry for delivery of substances across the skin in small ''bubbles'' made from fatty acids.
Fatty acid:
http://biology.clc.uc.edu/graphics/bio10...20acid.jpg
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#3

Would anyone mind giving examples then, of "small, lipid soluble molecules" ?

I wish there were a simple chart of different chemicals and their ability to penetrate the skin; I've looked all over!
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