[Lotus]

Pharmacokinetic Interactions of Herbs with Cytochrome P450 and P-Glycoprotein 
http://downloads.hindawi.com/journals/ec...736431.pdf

concurrent use of drugs and herbal products is becoming increasingly prevalent over the last decade. Several herbal products have been known to modulate cytochrome P450 (CYP) enzymes and P-glycoprotein (P-gp) which are recognized as representative drug metabolizing enzymes and drug transporter, respectively. us, a summary of knowledge on the modulation of CYP and P-gp by commonly used herbs can provide robust fundamentals for optimizing CYP and/or P-gp substrate drug-based therapy. Herein, we review ten popular medicinal and/or dietary herbs as perpetrators of CYP- and P-gp-mediated pharmacokinetic herb-drug interactions. e main focus is placed on previous works on the ability of herbal extracts and their phytochemicals to modulate the expression and function of CYP and P-gp in several in vitro and in vivo animal and human systems. 


Medication & Herbal Inhibitors of the Cytochrome P450 (CYP) Enzymes Drug 
https://www.ebmconsult.com/content/pages...inhibitors

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This is positive step forward in identifying herbal pathways. 
L.