[bettie32]

Hi Bettie, 

I looked at the site you listed, I couldn't find any evidence (other than a theoretical observation) supporting their claim that Astaxathin promoting T.

Because this supplement may inhibit the 5-alpha-reductase enzyme, it could cause side effects similar to other compounds that also inhibit this enzyme. These effects are theoretical and have not been demonstrated in human research trials.

I don't think ladies need that much pro-aromatase, see woman get aromatase (endogenously) or occurring naturally from ovaries, plancenta, the synthesis of FSH (follicle stimulating hormone) via the negative feedback loop , the pituitary, in adipose (human fat)

However, I think preadipocytes  (pre-adipose) cells are better suited for breast development rather than mature adipocytes (or stored fat)...a topic for another day maybe.


Anyways, preventing DHT is completed in multiple pathways,.....my theory is that the more you inhibit DHT (or limit its access to these pathways) via 5 alpha reductase, leaves hormones to freely distribute (or synthesize) naturally........aka up-regulation to the aromatase enzyme.

Apologies for the complexities,....we are the Kings and Queens of NBE   And....it is in the science we find breast growth. 




Here's a human trail though.

A preliminary investigation of the enzymatic inhibition of 5alpha-reduction and growth of prostatic carcinoma cell line LNCap-FGC by natural astaxanthin and Saw Palmetto lipid extract in vitro.

J Herb Pharmacother. 2005;5(1):17-26.
Abstract
Inhibition of 5alpha-reductase has been reported to decrease the symptoms of benign prostate hyperplasia (BPH) and possibly inhibit or help treat prostate cancer. Saw Palmetto berry lipid extract (SPLE) is reported to inhibit 5alpha-reductase and decrease the clinical symptoms of BPH. Epidemiologic studies report that carotenoids such as lycopene may inhibit prostate cancer. In this investigation the effect of the carotenoid astaxanthin, and SPLE were examined for their effect on 5alpha-reductase inhibition as well as the growth of prostatic carcinoma cells in vitro. These studies support patent #6,277,417 B1. The results show astaxanthin demonstrated 98% inhibition of 5alpha-reductase at 300 microg/mL in vitro. Alphastat, the combination of astaxanthin and SPLE, showed a 20% greater inhibition of 5alpha-reductase than SPLE alone n vitro. A nine day treatment of prostatic carcinoma cells with astaxanthin in vitro produced a 24% decrease in growth at 0.1 mcg/mL and a 38% decrease at 0.01 mcg/mL. SPLE showed a 34% decrease at 0.1 mcg/mL.
CONCLUSIONS: Low levels of carotenoid astaxanthin inhibit 5alpha-reductase and decrease the growth of human prostatic cancer cells in vitro. Astaxanthin added to SPLE shows greater inhibition of 5alpha-reductase than SPLE alone in vitro.

PMID 16093232 [PubMed - indexed for MEDLINE]

Anti-cancer potential of flavonoids: recent trends and future perspectives
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824783/

Thank you, Lotus for replying and for the info <3
I get paranoid because the last thing I want to do is increase testosterone! I was also thinking of going for Saw Palmetto too but keep reading that though it decreases DHT, it also decreases estrogen. It's very confusing.
And I also read about studies stating that taking astaxanthin with saw palmetto decreases DHT and estrogen, while raising testosterone!!    :
http://www.mercola.com/testosterone.aspx#6

As of now, I'm more inclined towards astaxanthin. It is a great antioxidant after all....I guess the only way to find out is to try :o)