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Negative Side Effects from PM

#11

Makes me wonder sometimes if implants are actually safer...I think it's foolish to undergo an unnecessary operation..but then again playing with hormones doesn't seem much wiser either...sorry, lately I've been a bit paranoid about safety and all that...reading lots of articles about estrogen and breast cancer and stuff ....Sad
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#12

Well, yes, that's exactly my point. I've been paranoid because my best friend is actually a litigator against the pharma industry pushing estrogen as hormone replacement therapy. I guess I heard too many horror stories from her, so now I am worried about excess estrogen.

Knowing me, I'm actually desperate enough to try PM just to see if it works, but I can't find accurate info about how much estrogen it contains, and what the side effects are from prolonged exposure. I'm sure that 2 months isn't enough time to see significant breast growth, and stopping taking it probably reduces size of breasts, so what is the point?
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#13

Actually I found an interesting article about PM...but as with everything out there you can't know if it's honest or just trying to sell a product...so here's the interesting part:

"Can Anything Be Done About Estrogen Dominance?

The incidence of breast cancer in the United States is 141.1 and the incidence of breast cancer in Northern Thailand(Chiang Mai Province) is 13.7. Most of the males and females in this province consume a phytoestrogen herbal substance called Pueraria mirifica PM. This plant has a tuberous root which can be eaten. The plant appears identical to other local plants and can only be distinguished from other non-PM containing plants during the 2 weeks annually when it is flowering. Most of the PM being sold is misidentified and has none of the benefits of PM.

PM contains a valuable phytoestrogen named miroestrol. Miroestrol is similar to the safest human estrogen estriol. Miroestrol is 3000 times stronger than the estrogenic activity exhibited by soy isoflavones(genistein). PM has more than 1000 times the estrogenic activity of red clover. In addition to miroestrol PM contains substantial amounts of other phytoestrogens including daidzein, genistein, puerarin, and mirificin.

When miroestrol enters an estrogen receptor it modulates the effect on the receptor. PM supplements when the estrogenic activity is low and dilutes if the receptor estrogenic activity is high. Miroestrol has no effect on estrogen levels in the body as it only influences the estrogen receptor.

In a clinical study on menopausal women in Thailand miroestrol lowered hot flashes 11 fold and night sweats 4 fold within 30 days. Most women start to notice relief of symptoms within one week.

Approximately 70% of Japanese women taking PM noted an increase in breast size. This was more apparent in younger women than older women.

The dosage of PM in females was 2 mg. per kilo of body weight. In the first month of therapy for menopausal symptoms 3 mg can be taken. Each pill of Beyond Hormone Replacement Therapy HRT contains about 80 mg. so taking 3 pills would supply this. A U.S. woman weighing 70 kilos should take one pill 80 mg. twice daily. In the clinical studies in Thailand doses no toxicity was noted even in doses 2000 times the usual dosage. Traditional Thai usage has menstruating women skip the therapy during menses.


So basically according to this PM is actually good: supplements when the estrogenic activity is low and dilutes if the receptor estrogenic activity is high PM would actually regulate estrogen, so it's not possible to be estrogen dominant because of PM, if you're low on estrogen it gives you estrogen, if you're high on it, it dilutes it..but of course as you can see there is a product mentioned at the end (it's interesting the product is called Beyond hormone replacement therapy, since you mentioned that)...but the article seems legit, full of info, you can read the entire article here, it's got interesting info about cancer: http://www.newswithviews.com/Howenstine/james56.htm

Another part I found interesting was this one: appears identical to other local plants and can only be distinguished from other non-PM containing plants during the 2 weeks annually when it is flowering. Most of the PM being sold is misidentified and has none of the benefits of PM.
It makes me wonder about all the debate that's been going around because of wild vs. farmed PM....
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#14

That's an excellent article. Thanks for posting this. I think many of us are confused about estrogen, its safety and the difference between herbal and synthetic estrogen. Now I might actually try PM. Did you ever take it?
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#15

Oh well, just three minutes after posting the above, I came across this article, and I quote "Estrogen has little if anything to do with increasing breast fat stores. "

http://www.totalityofbeing.com/Frameless...tShape.htm

Basically, the article states that progesterone is the hormone to supplement for breast growth, not estrogen. From past experience, estrogen birth control pills have never produced breast growth for me, but I never tried progesterone before.

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#16

Well I'm on my second month of PM and I am growing so I do believe you can grow from it...actually I had read that what progesterone did was give the breasts a rounder appearance and estrogen was responsible for the fat storage...
Anyway here are two more articles :

http://www.ncbi.nlm.nih.gov/pubmed/15886524?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=8
http://www.ncbi.nlm.nih.gov/pubmed/17870258?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=18

And I've read somewhere that PM acts like tamoxifen: http://en.wikipedia.org/wiki/Tamoxifen
Tamoxifen is used in breast cancer treatment....

But not sure, I'll keep investigating Smile
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#17

Update: I just completed my first week on PM, and my breasts have shrunk drastically! I first thought that I am imagining this, but the tape measure doesn't lie. I am down 2 cm! I am also not holding on to any swelling- it disappears much faster.

I checked the Noogleberry forum and someone posted that this could be due to estrogen dominance. Apparently PM does not work well for estrogen dominant women? There was also a link to Dr Lee's hormone test to determine if one's hormones are balanced:

http://www.johnleemd.com/store/resource_...etest.html

This shows that I am in fact estrogen dominant. Now what? Stop taking PM? Is there an herb that works better for estrogen dominant women? Confused.
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#18
Sad 

Hi girls,

Thanks for all the articles, it really helps trying to make sense of everything, although as soon as I read one, something else is bound to confuse me again, lol.

Talking of which, I've been on the progesterone only injection for 18 months, so have all the progesterone I could ever want, I would imagine, and no breast growth - sorry to disappoint anyone.

I also did the Dr Lee test and I'm estrogen defficient. I'm thinking "huh, I've then gone and loaded my body with the progesterone injection...."

I've been taking PM since May 13th, and the first week I grew an inch, I'm not kidding, I looked at my before photo, and thought, "oh my god, I'll be done in a month or so" I then bought the cream from the same supplier, and I don't know if this was the reason why, but I lost the inch Dodgy

I used up that bottle of pills but stopped using the cream (both from pueraria-uk) and am now taking Thanyaporn 350mg x3 per day (sometimes x2 as I forget at lunch).

I'm not growing Huh and it has crossed my mind to wonder if this is because it's not farmed so can't be certain of it's potency.

Adrianna, was it Siriporn you were taking at first when you were growing? I don't know whether to try that, or the stronger Ainterol, or the Biovea cream that Portia74 had success with.

Help!? Huh

I hope you manage to break your plateau, keep the faith, because you know that you did grow, so something can be done, it's just hard to figure out what.
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#19

Yes, I've always used Siriporn and I'm still growing from it..I really think topicals are very important so a good PM cream is the best you can do...I'm currently taking only 100 mg of PM internally but the PM cream keeps me growing..one thing I recommend for breaking plateau is massage, after I started massaging with the bust roller on my second month I got a growth sprout
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#20

Hi guys is anyone still using PM?
I'm like most of you so lost and confused and scared with all the different info, just going crazy.
But after spending many nights on the internet researching about PM and natural breast enlargement in general I finally (after many months) decided to buy PM the ainterol brand. I'm still scared as the reviews are both positive and negative. I don't know what to expect but I'm desperate for some growth. It sucks having tiny boobs and I'm sick of it.

So please respond if anyone is still using it or any updates. Once my package arrives I'll start taking the pills and will let you guys know how I'm going.

This is my first post btw. I'm so new to this.
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