[SerraSun]

Ah, here's something.

{from http://eyelighteningforum.forumotion.com...lightening )

MSM alone isn't going to do much. You're going to want a melanin inhibitor like turmeric or chamomile. Boil a teabag of chamomile in a small amount of water. Put turmeric powder in a napkin or whatever those coffee paper things are called...when they use em to make coffee...? and do the same thing..as if you were making turmeric tea. Those together with some saline solution should be used after MSM drops...MSM opens the pores in your eye up and allow ingredients to penetrate better. Turmeric and chamomile inhibit melanin production. Honey has lightening properties...but honey will sting, as will the MSM. You can add honey to the chamomile/turmeric drops...but not too much because you don't want your eye burning to death.

Permanent is unknown. The experienced guy on there (the green eyed fellow) believes that the melanin is pretty much gone permanently. It would seem likely to me that his eyes would darken a bit over the years if he didn't maintain them with drops...but overall, I don't think if you lightened to the extent of green/blue, your eyes would ever go back to being their natural dark brown again.

It takes a very long time. He originally had a dark brownish hazel. It took him 3 years on some herbal drops (probably containing melanin inhibiting junk like chamomile) to get to light brown...and then his eyes lightened extremely fast after he discovered the use of MSM drops. It took him 2 months to get to the light green you see now after the 3 years of herbal drops. He estimates it'd probably only take him 3 months to get from green to blue if he wanted to. Once your eyes have gotten rid of that first, strong layer of melanin, the lightening process seems to be super fast.

The gal I posted a page or two before this with the dark brown -> noticeably light brown eyes took 6 months of chamomile & honey drops. She did not use MSM or turmeric.

The problem with this whole lightening thing is:

1. Your eyes are so valuable and sensitive to the range of ingredients you can use in eye drops is very limited.

and

2. There's really no known or tested method for speeding up cell turnover rate. If there was something for that, I'm sure the lightening process would be much faster.

RESEARCH:

Fungus breaks down Melanin
Certain fungus extracts actually break down current melanin. Currently, this is still a new development, but they hope to use them in natural skin lightening creams and hair bleaching products in the future. The extracts are expensive and nearly impossible to acquire.

Also, I just don't think it's a good idea to put random fungus powder eye drops in your eye.

Iris Melanin
The key to iris lightening, it seems, is to deal with current melanin. Skin lightening creams are mostly ingredients that inhibit melanin synthesis and speed up cell turnover. Because our skin melanocytes are extremely active and would be put to work if you went out to the beach tanning, it's easier to just inhibit this process and increase cell turnover to get rid of tanned skin.

Unfortunately, this means there's little products out there that breakdown melanin or destroy melanocytes.

The melanin in our iris is usually done being created around 3 years of age. This is why blue eyed babies can sometimes turn out with green or brown eyes.

When we go out in the sun, our irises aren't usually being exposed to complete direct sunlight like our skin is. Think about it. If the sunlight hits our skin, it's not a big deal. Then our skin gets to work with creating melanin more because the UV rays destroy melanin.

If the sunlight hits our eyes directly, it's uncomfortable and we squint, and look away. Our irises are protected by the shadow of our brow bones, eyebrows, eyelids, and eyelashes.

Bottom line:
Melanin synthesis is not needed to protect the iris from sun damage. So iris lightening results will be, for the most part, permanent.

Dealing with Iris Melanin
The only commercially used 'depigmenting' agent for skin is monobenzone, the monobenzyl ether of hydroquinone. It's used for patients with vitiligo to help speed up the process of depigmentation so they can hurry up and get pale, and get out of the awkward spotty phase. The problem with this is that it affects areas near its application. The risk of putting monobenzone powder in saline and applying them is that you don't know how it'll affect the skin around the eyes. You don't want depigmented spots appearing around your eyelids.

Fungus extracts, like discussed above, breakdown melanin, essentially getting rid of pigmentation (although not permanently, because I don't think they destroy melanocytes like monobenzone does) but is innaccessable and relatively new. So scratch that as well.

That leaves us with hair bleaching agent, hydrogen peroxide. No, you shouldn't go pouring it into your eye. Honey contains an enzyme that activates upon contact with body fluid that produces hydrogen peroxide.

Manuka honey has more hydrogen peroxide capabilities than regular store-bought honey, but Jarrah honey (from Australia) has 50-70% more hydrogen peroxide strength than Manuka. You can order it online.

Lemon is also a natural bleaching agent, but stings like hell. You'd want to dilute it a LOT with saline. I think Jarrah honey would suffice.

To increase cell turnover, I'd use Aloe Vera Powder in saline.

My theory is this:

Breakdown melanin by bleaching with Jarrah honey and/or lemon for 5 days of the week. Then use MSM and Alpha Arbutin (potential helper of flushing out weakened melanin cells) for a day. Then use Aloe Vera for the next day to speed up cell turnover. Repeat this for several weeks, and I wouldn't be surprised if the results were faster than this 5 year bs.

They have a laser coming out in 18 months for Europeans, 3 years for United States. It'll be called Lumineyes, google it. It destroys the melanin, and your body naturally flushes it out for 2-3 weeks then you'll have blue eyes. But at $5000 for a couple zaps, I say hell no to that. Plus I wonder if everyone would have the same looking blue eyes from that procedure…

I think melanocytes are more active at a young age, because that's when you're first exposed to light. After adjusting, your eye color isn't going to change much. I know there's exceptions especially among hazel/green eyed people, but they typically aren't super significant changes. Melanocytes become a lot less active, it seems, after youth. This would explain why a lot of eyes lighten ever so slightly over time, though most probably aren't significant enough to really notice changes. They could become active again at certain periods of life (like puberty, and other periods where people with blonde hair experience darkening)

Increased sun exposure over the years + moderately inactive melanocytes = a little bit of melanin cell destruction = lighter eyes. (typically. there will always be exceptions. also, most races with tons of melanin in their eyes [indian, asian, african] probably won't lose enough melanin in their life time to notice a change)

A person with brown eyes or even green eyes isn't going to lighten to blue eyes with age alone. It apparently has happened before, but that'd be a very rare, exceptional case.

But, you can tell melanocytes in the iris are a lot less active than one in skin because:

If you go to the beach for a week and tan in the nice sun, you'll notice by the end of the week you'll be a few shades darker as far as skin, and your hair with have a sun-kissed effect as well (yes, even dark haired people) and for gingers/super pale people, you'll sunburn of course, lmao.

But your eyes (alive cells, not dead like hair..so theoretically would darken with sun exposure) are probably not going to be significantly darker, even though your whole body was exposed to sun rays for long periods of time. If there was a significant change/eye color 'tanning', people with light eyes would report it and be avoiding the sun like the plague.

So unlike skin lightening, you don't need to be as worried about stopping melanin synthesis. The quicker way would be to find a melanin cell destroying agent safe for eyes.

Use MSM drops to help penetration -> Use melanin cell destroying agent -> use melanin inhibiting agent to prevent the bit of melanin production that might be going on after melanin cell destroying -> use something to increase cell turnover rate so that the process is sped up.

We have MSM, and we have inhibitors.

Melanin cell destroyers:

Remember, we don't want to kill melanocytes. That could potentially cause a lot of problems. We just want to kill the melanin cells that they have produced. I'm having a hell of a time finding ones.

Monobenzone is used for patients with vitiligo, but it apparently kills melanocytes, melanin, everything. It's probably way too powerful to use in your eye. Although you'd probably use a very low concentration, it apparently gets in the blood and produce depigmenting elsewhere. (in spots) I doubt the concentration you'd use in your eyes would be powerful enough to really cause noticeable change in your skin, but still.

http://www.askmehelpdesk.com/skin-lighte...441-4.html

I guess people using it on their skin experience iris lightening. Some are probably more sensitive to it than others. The person saying it doesn't change your eye color clearly doesn't know what the hell they're talking about. "Scientists haven't reported that so it can't be true!!" LOL.

You can see that these people are applying it at high concentrations. I'm thinking you'd definitely want less than 1% concentration in your eye to prevent the amount in the blood causing depigmenting elsewhere, noticeably. Also, it'll probably sting if it's at something like 10%.

That's all I found for now.

Cell Turnover rate increasing agents

Looking in the acne community as well as lightening community, it's safe to say these agents increase cell turnover rate:

Retinoids (cell turnover exfoliate) <---variations of vitamin A
Salicylic acid (exfoliate)
Aloe Vera
Biotin

Anything that exfoliates is going to speed up the process as well.

Okay obviously we don't wanna put any acids in our eye.

Conveniently enough, people with dry eye problems seem to work with retinoids and aloe vera.

Drops with vitamin A:

http://www.amazon.com/Viva-Drops-Lubrica...roduct_top

Unfortunately, since they're doctor recommended, you'd have to buy them online. But whatever.
And mixing some pure aloe vera gel or juice (NOT one with alcohol) with saline could probably help.

The key to anything is diluting with saline. Even if it's something that will burn, like MSM, it's not going to burn your eye to blindness/injury if it's diluted. (unless you're trying to put bleach in your eye or something) But I don't condone adding in mysterious chemicals to your eyedrops. Trying things out from researches is different with bones. With eyes, it's a lot more dangerous territory, so be careful.

Don't buy a lot. You'll be using a very very tiny amount in each solution you prepare so a medium-ish sized bottle of it should last you for this whole process.

A BRIEF GUIDE

MSM: Is a carrier. It will penetrate through the skin, and carry other ingredients with it. But does not do much, if anything, to lighten.
HONEY: Lightens because it creates natural hydrogen peroxide when it mixes with your tears. But will not block the formation of new melanin.
AA: Is the lightener used in most skin lightening creams. It blocks the formation of melanin.
Turmeric: Is up to ten times stronger than AA according to some studies. It blocks the formation of melanin.
Chamomile: Is a lightener, often used to naturally lighten hair. According to some it also inhibits melanin production.

I'm gonna stop posting from the site since it's pretty easy to register. I'm still waiting for a reply from eyecolorboard....