[Candace]

I added the Sapien progesterone program and was surprised to find that it has eliminated my calf edema. I was under the impression that progesterone would just counter estrogen-induced edema, and my edema's not from estrogen, but rather from mold VOCs -> brain overreacts, stresses out, and releases aldosterone. It turns out that progesterone will treat any kind of edema because progesterone binds to the mineralocorticoid receptor tighter than aldosterone and inhibits it.