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Hormones, receptors and anatomy; definitions and abbreviations
#1
IGF-1 = Insulin growth-like factor 1
Prl = Ptolactin
PrlR = Prolactin receptor
ER = Estrogen receptor
ER-alpha ERα or ER-α = Estrogen Receptor Alpha
PR = Progesterone Receptor
PRB = Progesterone Receptor B
GH = Growth Hormone
GHR = Growth Hormone Receptor
SERM = Selective Estrogen Receptor Modulator; means it interacts with ER
SPRM = Selective Progestin Receptor Modulator; means it interacts with PR
Agonist = encourages activity
Antagonist = discourages activity
Downregulation = Reduction in receptor proteins, decreasing sensitivity
Upregulation = Increase in receptor proteins, increasing sensitivity

LH = Luteinizing Hormone
FSH = Follicle Stimulating Hormone

The words progestin, progestogen, and progesterone are often used interchangeably in science literature
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#2
undefined
Let it grow ♬
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#3
Receptors:
* PrlR - Prolactin receptor --- contained in nipple and areola
* ER - Estrogen receptor
* ER-alpha - ERα - ER-α - Estrogen Receptor Alpha --- contained in milk ducts
* PR - Progesterone Receptor
* PRB - Progesterone Receptor B --- contained in cooper's ligaments, and mammary glands
* GHR - Growth Hormone Receptor
* CaSR - Calcium Selective Receptor --- regulates calcium for purposes of breastfeeding

Hormones:
* IGF-1 - Insulin growth-like factor 1
* Prl - Prolactin
* LH - Luteinizing Hormone
* FSH - Follicle Stimulating Hormone
* GH - Growth Hormone
* DHEA - Dehydroepiandrosterone
* Estrogens are a class of hormones.
** E1 - Estrone - oestrone
** E2 - Estradiol - oestradiol - 17β-estradiol
** E3 - Estriol - oestriol
** E4 - Estetrol
** Phytoestrogens - plant based estrogens
** Mycoestrogens - fungal based estrogens. The prefix myco means having to do with fungi. Red Reishi would contain mycoestrogens.
* The words progestin, progestogen, and progesterone are often used interchangeably in science literature.
** Progesterone - P4 - is a specific hormone.
** Progestogens are a class of hormones that include progesterone. The term progesterones, sometimes refers to all progestogens. Progestogens are not estrogens.
** Progestins often refer to synthethic progestogens.
** Phytoprogestins, phytoprogestogens and phytoprogesterones have the same meaning, they mean plant progestogens.
* Phytohormone - plant based hormone.
* Mycotoxin - toxin from fungal sources; Mycotoxin is NOT mycoestrogen. ZEN contains both mycotoxins and mycoestrogens.

Terms:
* SERM - Selective Estrogen Receptor Modulator; means it interacts with ER
* SPRM - Selective Progestin Receptor Modulator; means it interacts with PR
* Agonist - encourages activity
* Antagonist - discourages activity
* Downregulation - Reduction in receptor proteins, decreasing sensitivity to hormones
* Upregulation - Increase in receptor proteins, increasing sensitivity to hormones

Anatomy:
* Mammary glands - milk producing glands or lobules
* Cooper's ligaments - ligneous tissue that connects from the extent of the pectoral muscles, and supports the breast
* Milk ducts - ducts that transfer milk from the mammary glands to the nipple
* Areola - surrounds the nipple
* Mongomery's or Areolar glands - glands located on the areola to lubricate the nipple and areola

       

Updated post from Hormones and receptors; definitions and abbreviations
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#4
Lovely, I like the this list, it will help new and existing BN members.

Can you add the target tissues to each group? Smile


* AR - Androgen Receptor
** T - Testosterone
* SHBG: Sex Hormone-Binding Globulin
* AI - Aromatase inhibitor
* AA - Anti-Androgen
* GABA: Gamma-Aminobutyric Acid --- A protein which is a neurotransmitter
* LT: L-Tyrosine
* PABA: Para-Aminobenzoic Acid
* 5ar - reductase, converts testosterone into DHT


♦NBE Formula→Free Testosterone→5 alpha inhibitors→Aromatase→E1/E2....DNA→RNA→Protein ♦
♦Regulation of Estrogen & Progesterone-Hypothalamus→GnRH→Pituitary→FSH→Follicle→Estrogens ♦
♦ego cogito, ergo sum TG.
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#5
It's been updated.

AR - Androgen Receptor
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#6
Estrogen Dominance - theory that the proportion of estrogen is high and unbalanced compared to progesterone. There are symptoms believed to be associated with Estrogen Dominance.

Aromatase - enzymes that converts androgens into estrogens. This is a major path for estradiol production.

DHT - Dihydrotestosterone is a potent androgen that cannot be converted into estrogens. DHT inhibits breast growth. It also goes by 5α-dihydrotestosterone (5α-DHT), androstanolone (5α-androstan-17β-ol-3-one) or 17β-hydroxy-5α-androstan-3-one
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#7
* 5-alpha-reductase - 5α-reductase --- converts hormones into much powerful dihydro forms.
* Corpus Luteum --- a temporary organ that creates progesterone and relaxin. It's purpose is to signal the body to keep the egg or fetus. There is a positive feedback loop between the pituitary gland to release prolactin and the Corpus Luteum, to signal the body not to start menstruation. The corpus luteum dies by the start of menstruation and it eventually disintegrates within the ovary.
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#8
Lotus Wrote: * AR - Androgen Receptor
** T - Testosterone
* SHBG: Sex Hormone-Binding Globulin
* AI - Aromatase inhibitor
* AA - Anti-Androgen
* GABA: Gamma-Aminobutyric Acid --- A protein which is a neurotransmitter
* LT: L-Tyrosine
* PABA: Para-Aminobenzoic Acid
* 5ar - reductase, converts testosterone into DHT


Above is contribution by Lotus; Sunday, February 22, 2015
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#9
This thread has been merged February 23, 2015.

New updated thread is at: NBE Glossary: Scientific Glossary: Anatomy, Receptors, Hormones, Enzymes, Terms, etc.
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#10
(26-09-2014, 08:44 AM)lovely11 Wrote: Receptors:
* PrlR - Prolactin receptor --- contained in nipple and areola
* ER-alpha - ERα - ER-α - Estrogen Receptor Alpha --- contained in milk ducts
* PRB - Progesterone Receptor B --- contained in cooper's ligaments, and mammary glands

corrections to above.
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