[surferjoe2007]

Hey again, as you mentioned Ibutamoren and also have a thread on IGF I have another question popped up: in my country's articles it's higly advised to take it not every day but on 3/3, 4/4 etc regimen since they claim one gets used to the subtsance pretty fast and the effect stops. However, I havent really seen people mentioning it elsewhere, apart from general advice to cycle it eventually if you're using it long term. I believe you somewhat researched the topic so have you seen any significant scientific data to support the claim I read about (the necessity to have days-off every 3 days or so)? I wonder if it's just misinformation based on a single "study" or smth..
PS. I saw people mentioning strong cravings as a side effect, I've been taking it for 5 days so far and dont experience it at all, I wonder if it means it's not working or that my subtsance is bad.

Not many have tried it for NBE yet.  You may want to ask the couple of forum members that have .  I think MissMadScientist is one.  You can also find lots of info in bodybuilding forums, though it's primarily for muscle gain and workout recovery.  I think there was a one year study on it and I assume they took it every day.  They are studying it more for the regenerative youthful properties, since it increases both growth and regeneration of old tissue.  Probably muscles, joints, breasts, brain, heart, everything.  Extra cell replication does carry a small increase in cancer risk though, especially for the elderly.  So while the 1 year study found hardly any risk, who knows what more study will find, and this still is a drug that has not yet been approved and is illegal for human consumption.  Do what you do as your own decision and at your own risk.

Cravings are different for different people.  You could check bodybuilding forums.  It could depend on the dose, and it could also take more days to set in.  Though after several more days the sensation may lighten too.  Mk-677 causes release of ghrelin, the hunger hormone.  So hunger is more of the main effect than a side effect.  But ghrelin also leads to the immediate use of all that ingested food which causes all the growth/regeneration effects, boosted metabolism and increased growth hormone.  If anything on its own it causes weight loss rather than weight gain, unless you overeat to match.  But the feeling of hunger could be strong or weak for different people.  And most of the fakes boost hunger as much or more too, as part of their trickery.  There's an anabolic steroid that causes a huge appetite increase for example.  I'm not sure how common or uncommon fakes are now though, especially as mk-677 gets cheaper.