[RaineMail]

Yeah, definitely something to taking them all at once at night. My breast are bigger and fuller in the morning and it's last so far til now. I've been taking them around 9:30ish before I go to bed and notice an amazing difference in the morning. I'm actually debating if I should keep doing this, even after I'm not so busy (I hope soon) or if to go back to the 4x a day. 

Both have given me good results. Hmmm I'll think on it. But for now it's the all at once at night method anyways.

I've read in several places to take all of them at once. That throughout the day just exhausts the estrogen receptors in your body. So once a day (especially if things are growing better at night) at night seems to be the best option.