[HopefulKitKat]

Oral (E2) estrogen impairs IGF-1 in the liver.
http://www.breastnexus.org/showthread.php?tid=28234

If anything keep the thread here, if that doesn't work let me know and I'll move it.

Yayyy, Lotus! I was hoping you'd shed some light! Thank you so much!
I'd personally prefer the thread's name and location to be changed since this pertains to nearly all aspects of NBE, but if it's too much trouble and you feel it's fine here then that's okay.

So back on topic, does this mean we shouldn't take oral forms of estrogen at all if we can get topical alternatives? What if we can't get those alternatives, would it still be worth taking oral estrogen if it ultimately inhibits growth? Also, this may be a jump in logic, but since oral testosterone has the opposite effect on IGF-1 (?), would that mean taking oral forms of anti-DHT and testosterone have a similar effect on the liver as estrogen? Or I guess not since they indirectly affect estrogen outside the liver, huh?
Just thought I'd get all my dumb questions out the way now.