30-09-2012, 02:44 AM
(This post was last modified: 30-09-2012, 02:49 AM by mochaccino.)
Apparently there's only ever been one identified case of true estrogen insensitivity, and the article I read implies that the results of true estrogen insensitivity would be very severe and noticeable. I wonder if instead, in women like me and lled, our bodies are just massively over compensating for the excess estrogen by pumping out loads of SHBG, or down regulation is occuring at an unusually fast rate, or some other compensating mechanism I could never even think of. Of course, none of those other explanations are necessary if it turns out that we just have low E. NVMD the possibility that are issue are entirely different. Besides, lled and I are not the only women who have ever had a very muted response to PM. I wish I could remember their usernames. If low E is not the cause of a lack of response to PM, than it really is a big mystery.