30-04-2010, 05:32
As a quick answer, it doesn't effect your normal hormones because they are not passing through your digestive tract . The chemical in GFJ acts an an inhibitor of a certain enzyme which is affected by only SOME things. In the NBE case, the herbs you are taking have phyto-estrogens in them and since they are metabolized (hopefully) and the enzyme that would normally stop them is temporarily allowing them to pass into the system, that is a good thing. This isn't going to make you crazy and balloon your hormone system. The effect is 28% or so, depending. So , if you took a 640 mg cap of SP, the effect you might get would be like 820 mg, so you could take 3 pills instead of 4.
There are a number of investigations going on by doctors to use this to advantage by prescribing lower doses and letting the action of the GFJ provide the body with the boost--this could be very good especially where very expensive drugs are concerned.
This isn't turning a firecracker into a hydrogen bomb. This enzyme action is what you want in any case and that's is where any herbs are generally going to be processed. Milk Thistle is one such herb that also falls in the NBE column but in reality it also inhibits the 3A4 enzyme and may be allowing something else to work, rather than being the main chemical.
The body has to do some manipulation of these herbs if NBE is going to work. GFJ and grapefruit have been around for a long time and there haven't been any reports of women jumping out of windows after breakfast. As with all things, people should follow what they believe to be the safest course--I'm not pushing anything here, just providing some information that I think is useful.
There are a number of investigations going on by doctors to use this to advantage by prescribing lower doses and letting the action of the GFJ provide the body with the boost--this could be very good especially where very expensive drugs are concerned.
This isn't turning a firecracker into a hydrogen bomb. This enzyme action is what you want in any case and that's is where any herbs are generally going to be processed. Milk Thistle is one such herb that also falls in the NBE column but in reality it also inhibits the 3A4 enzyme and may be allowing something else to work, rather than being the main chemical.
The body has to do some manipulation of these herbs if NBE is going to work. GFJ and grapefruit have been around for a long time and there haven't been any reports of women jumping out of windows after breakfast. As with all things, people should follow what they believe to be the safest course--I'm not pushing anything here, just providing some information that I think is useful.