SHBG is a protein, and some proteins are/have receptors. So that can make sense that SHBG can be up/down-regulated. The other term of regulation isn't being used to the same meaning as de/re-sensitization of cell receptors. up/down regulation, also meaning (de)sensitization, is for hormone receptors, which are on proteins on cells.
5-alpha-reductase is an enzyme, but I'm unsure if it is a receptor or protein. It seems like 5AR is.
5-alpha-reductase is an enzyme, but I'm unsure if it is a receptor or protein. It seems like 5AR is.