16-01-2016, 14:52
GABA may help women 30 and older who are doing NBE
March 17 2006 at 10:00 PM
Sunset (Login liquidSunset)
EVE MEMBERS
hey ladies, I have read about this stuff called GABA. Lemme give you some info that may be the very "boost" some of you need:
Other than estrogen,progesterone,prolactin,and testosterone there is one more "ingredient" to consider: GROWTH HORMONE.
There is no such thing as a "growth hormone pill" The only way to get a growth hormone supplement into your system is through an injection that costs about $10,000 PER MONTH! A more practical solution would be to INCREASE your bodys own natural production of growth hormone. This can be done in 2 ways:
1. By supplementing with GABA
2. By improving your diet,exercise, and sleep habits.
SUPPLEMENTING WITH GABA:
GABA is recommended for women over the age of 30. By taking a moderate dose of GABA before bed,you can easily boost your bodys production of growth hormone. It can even help you get a good nights sleep:GABA promotes sleep and relaxation so effectively, it is known as the brains "natural valium."
GABA is an amino acid (protien building block) that is naturally found in the body. GABA's job is to communicate messages through brain cells;there are large amounts of it found in the hypothalamus gland. Because the hypothalamus gland regulates the pituitary glad-which is primarily responsible for manufacturing growth hormone-researchers have discovered a link between GABA and growth hormone.
Since GABA is an amino acid, it can be made into a nutritional supplement from protien. Many studies haveproven GABA's ability to effectively increase growth hormone levels. In one study, researchers found that supplementing with GABA led to a 5-fold increase in growth hormone levels in only 90 minutes!
POSSIBLE SIDE EFFECTS
GABA is a safe, readily available supplement;side effects are rare. Some people noticed mild tingling around the face after taking GABA, but this effect is harmless and disappears after a couple of minutes.
Maybe this would help some of you out
SugarQ
(Login SugarQ)
SENIOR MEMBER
Re: GABA may help women 30 and older who are doing NBE
March 17 2006, 10:12 PM
Gaba is awesome stuff but there is a problem i keep facing. you dont actually need Growth Hormone itself for NBE. you need 1-IGF is what actually causes breast tissue growth. HGH just converts into 1-IGF in the liver. the differnce between the two is that HGH moves fat away from storing areas so when you excersise growth hormone will actually increase to help "burn" fat. 1-IGF will actually help to store fat. according to fawnmarie (from the beboard my on of my sources for HGH info) its this fat storing nature of 1-IGF that makes it Insulin like.
GABA is on source for supplimenting GABA but you cant take too much or you wont be doing yourself any favors. there are curtain times in the day when its benificial to take GABA. i will check and report back when i get more. but a peferred Suppliment for 1-IGF is Deer antler Velvet or Colostrum( make sure they have a fixed dosage of 1-IGF).
Sunset
(Login liquidSunset)
EVE MEMBERS
hmm..
March 17 2006, 10:17 PM
interesting, I never heard of that stuff. You can suppliment with deer antler velvet? Thats too cool My hunny hunts deer...lol
Thanks for the info SugarQ! So you can buy those supplements of it at a health food store?
SugarQ
(Login SugarQ)
SENIOR MEMBER
Re: GABA may help women 30 and older who are doing NBE
March 17 2006, 10:22 PM
Some Extra sources linking NBE to 1-IGF (sorry its a lil long lol but helpful)
-----------------------------------------------------------------------------
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9098173&dopt=Abstract
"Breast size in relation to endogenous hormone levels, body constitution, and oral contraceptive use in healthy nulligravid women aged 19-25 years.
Jernstrom H, Olsson H.
Department of Oncology, University Hospital, Lund, Sweden.
In 1993 and 1994, the relation between breast size and hormonal factors and body constitution was studied in 65 healthy nulligravid women aged 19-25 years. Twenty-five women were current oral contraceptive users, 20 women were former users, and 20 women had never used oral contraceptives. Breast size was strongly positively correlated with current oral contraceptive use during menstrual cycle days 5-10, as well as days 18-23. No significant effect of former oral contraceptive use was seen on breast size. A significant increase in breast size between cycle days 5-10 and days 18-23 was seen among current oral contraceptive users. Breast size was significantly positively correlated with body mass index (weight (kg)/height (m)2), height, and weight in nonusers (i.e., former and never users combined) but not in current users. In nonusers, during the follicular phase, breast size was significantly positively associated with insulin-like growth factor 1. During the luteal phase, larger breast sizes were significantly associated with higher 17 beta-estradiol and progesterone levels and lower testosterone levels among nonusers. In models for current users, large breast sizes were significantly associated with high prolactin and luteinizing hormone levels and low follicle-stimulating hormone levels during cycle days 5-10. During cycle days 18-23, larger breast sizes correlated with low endogenous progesterone levels.
PMID: 9098173 [PubMed - indexed for MEDLINE] "
-----------------------------------------------------------------------------
http://www.endotext.org/male/male14/male14.htm
"ESTROGEN, GH AND IGF-1, PROGESTERONE, & PROLACTIN
Estrogen and progesterone act in an integrative fashion to stimulate normal adult female breast development. Estrogen, acting through its ER a receptor, promotes duct growth, while progesterone, also acting through its receptor (PR), supports alveolar development (15). This is demonstrated by experiments in ER a knockout mice which display grossly impaired ductal development, whereas the PR knockout mice possess significant ductal development, but lack alveolar differentiation (28,6).
Although estrogens and progestogens are vital to mammary growth, they are ineffective in the absence of anterior pituitary hormones (13). Thus, neither estrogen alone nor estrogen plus progesterone can sustain breast development without other mediators, such as GH and IGF-1, as confirmed by studies involving the administration of estrogen and GH to hypophysectomized and oophorectomized female rats, which resulted in breast ductal development. The GH effects on ductal growth are mediated through stimulation of IGF-1. This is demonstrated by studies of estrogen and GH administration to IGF-1 knockout rats that showed significantly decreased mammary development when compared to age-matched IGF-1- intact controls. Combined estrogen and IGF-1 treatment in these IGF-1 knockout rats restored mammary growth. (23, 40). In addition, Walden et al. demonstrated that GH-stimulated production of IGF-1 mRNA in the mammary gland itself, suggesting that IGF-1 production in the stromal compartment of the mammary gland acts locally to promote breast development (49). Furthermore, other data indicates that estrogen promotes GH secretion and increased GH levels, stimulating the production of IGF-1, which synergizes with estrogen to induce ductal development.
Like estrogen, progesterone has minimal effects in breast development without concomitant anterior pituitary hormones; again indicating that progesterone interacts closely with pituitary hormones. For example, prolonged treatment of dogs with progestogens such as depot medroxyprogesterone acetate or with proligestone caused increased GH and IGF-1 levels, suggesting that progesterone may also have an effect on GH secretion (33). In addition, clinical studies have correlated maximal cell proliferation to specific phases in the female menstrual cycle. For example, maximal proliferation occurs not during the follicular phase when estrogens reach peak levels and progesterone is low (less than 1 ng/mL [3.1nmol}), but rather, it occurs during the luteal phase when progesterone reaches levels of 10-20 ng/mL (31- 62nmol) and estrogen levels are two to three times lower than in the follicular phase (42). Furthermore, immunohistochemical studies of ER and PR showed that the highest percentage of proliferating cells, found almost exclusively in the type 1 lobules, contained the highest percentage of ER and PR positive cells (42). Similarly, there is immunocytological presence of ER, PR, and androgen receptors (AR) in gynecomastia and male breast carcinoma. ER, PR and AR expression was observed in 100% (30/30) of gynecomastia cases (41). Given these data and the fact that PR knockout mice lack alveolar development in breast tissue, it appears as if progesterone, analogous to estrogen, may increase GH secretion and act through its receptor on mammary tissue to enhance breast development, specifically alveolar differentiation (28, 18).
Prolactin is another anterior pituitary hormone integral to breast development. Prolactin is not only secreted by the pituitary gland but may be produced in normal mammary tissue epithelial cells and breast tumors. (44, 25). Prolactin stimulates epithelial cell proliferation only in the presence of estrogen and enhances lobulo-alveolar differentiation only with concomitant progesterone"
-----------------------------------------------------------------------------
"Hormonal breast augmentation: prognostic relevance of insulin-like growth factor-I.
Hartmann BW, Laml T, Kirchengast S, Albrecht AE, Huber JC.
Department of Senology, University of Vienna Medical School, Vienna, Austria.
Many women would like to alter their breasts but are deterred by the risks involved. Silicone breast implants have been linked to a variety of illnesses, the most controversial of which are connective-tissue diseases. These circumstances urged us to perform this pilot study using a non-invasive method that involved the application of 17 beta-estradiol as it is known that estradiol enhances expression of insulin-like growth factor-I (IGF-I) which can promote growth in breast tissue. Forty-five women were included in the study. Their breast volume, IGF-I, prolactin (PRL) and estradiol levels were measured before treatment and between each application of 80 mg estradiol polyphosphate. The women's satisfaction with the results obtained was also subsequently evaluated. In 21 women (46.7%), breast size increased from 824.3 +/- 13.7 mm to 898.5 +/- 12.5 mm after 6 months. In these women a significant increase in IGF-I values was noted after 4 weeks of treatment. The increase in IGF-I values was not statistically significant in the remaining women. In addition, treatment was not successful in these women. IGF-I concentration seems to be of prognostic value as far as the response of breast tissue to estrogen stimulation is concerned. If IGF-I levels do not increase within 1 month, treatment should be discontinued. If IGF-I values do increase, this indicates that treatment is likely to be successful and can therefore be continued.
PMID: 9610425 [PubMed - indexed for MEDLINE]
Logged"
SugarQ
(Login SugarQ)
SENIOR MEMBER
Re: GABA may help women 30 and older who are doing NBE
March 17 2006, 10:28 PM
Important info about IGF suplimentation came from Fawnmarie
she said:
"Collostrum is an immune stimulant, but the best way to increase IGF is to understand how it's produced and take advantage of it.
IGF is produced in the liver from HGH. HGH is produced:
1) during the first 90 mintues of sleep
2) during intense exercise
3) when hungry
Things that suppress HGH production are:
1) sleeping on a "full" stomach
2) heavy sugar and starches
3) not waiting an adequate amount of time between meals.
After optimizing HGH production, then you need to turn attention to the liver, where IGF is made:
1) keep the liver clean (use liver cleanses)
2) eat an adequate amount of animal protein daily
3) avoid large amounts of alcohol on a regular basis
4) eat plenty of live, raw vegetables and fruits - apples and carrots are particularly good for the liver
If you are over 30-35, then you may want to consider supplements that increase HGH production - however be advised that they can increase the risk of cancer if it runs in your family or you have other risk factors.
Some supplements might include GABA, l'arginine or l'ornithine before bed (on an empty stomach). Be advised that GABA, in a small percentage of the population can cause physical side effects which are temporary, but mimic those of a full out anxiety attack (heart palpitations, flushing face, racing mind), and l'arginine can increase sensitivity in those with chronic pain conditions.
Fawn"
you can buy dear velvent and collustrum in any most health foods but you need to make sure that the IGF content is listed. a prefered brand is "NOW" IGF spray or losange but there are many others.
Sunset
(Login liquidSunset)
EVE MEMBERS
WOW
March 17 2006, 10:51 PM
Thanks SugarQ that is really interesting thANK YOU SO MUCH!
Sounds like it would be better than GABA, and did you see that she said GABA can cause permanet damage? I had no clue thank you! I am sure more ladies will find your info informative and interesting!
Sunset
(Login liquidSunset)
EVE MEMBERS
oops
March 17 2006, 10:52 PM
She said GABA side effects are temporary NOT permanant. But they mimic a heart attach?! Sounds no good
SugarQ
(Login SugarQ)
SENIOR MEMBER
yeah i recall reading that in her book
March 17 2006, 10:58 PM
I think i should check to see if 1-IGF suppliments have any negative effect too. im going to start looking.
Sunset
(Login liquidSunset)
EVE MEMBERS
ok
March 17 2006, 11:04 PM
thats always a good idea, thank you SugarQ.
March 17 2006 at 10:00 PM
Sunset (Login liquidSunset)
EVE MEMBERS
hey ladies, I have read about this stuff called GABA. Lemme give you some info that may be the very "boost" some of you need:
Other than estrogen,progesterone,prolactin,and testosterone there is one more "ingredient" to consider: GROWTH HORMONE.
There is no such thing as a "growth hormone pill" The only way to get a growth hormone supplement into your system is through an injection that costs about $10,000 PER MONTH! A more practical solution would be to INCREASE your bodys own natural production of growth hormone. This can be done in 2 ways:
1. By supplementing with GABA
2. By improving your diet,exercise, and sleep habits.
SUPPLEMENTING WITH GABA:
GABA is recommended for women over the age of 30. By taking a moderate dose of GABA before bed,you can easily boost your bodys production of growth hormone. It can even help you get a good nights sleep:GABA promotes sleep and relaxation so effectively, it is known as the brains "natural valium."
GABA is an amino acid (protien building block) that is naturally found in the body. GABA's job is to communicate messages through brain cells;there are large amounts of it found in the hypothalamus gland. Because the hypothalamus gland regulates the pituitary glad-which is primarily responsible for manufacturing growth hormone-researchers have discovered a link between GABA and growth hormone.
Since GABA is an amino acid, it can be made into a nutritional supplement from protien. Many studies haveproven GABA's ability to effectively increase growth hormone levels. In one study, researchers found that supplementing with GABA led to a 5-fold increase in growth hormone levels in only 90 minutes!
POSSIBLE SIDE EFFECTS
GABA is a safe, readily available supplement;side effects are rare. Some people noticed mild tingling around the face after taking GABA, but this effect is harmless and disappears after a couple of minutes.
Maybe this would help some of you out
SugarQ
(Login SugarQ)
SENIOR MEMBER
Re: GABA may help women 30 and older who are doing NBE
March 17 2006, 10:12 PM
Gaba is awesome stuff but there is a problem i keep facing. you dont actually need Growth Hormone itself for NBE. you need 1-IGF is what actually causes breast tissue growth. HGH just converts into 1-IGF in the liver. the differnce between the two is that HGH moves fat away from storing areas so when you excersise growth hormone will actually increase to help "burn" fat. 1-IGF will actually help to store fat. according to fawnmarie (from the beboard my on of my sources for HGH info) its this fat storing nature of 1-IGF that makes it Insulin like.
GABA is on source for supplimenting GABA but you cant take too much or you wont be doing yourself any favors. there are curtain times in the day when its benificial to take GABA. i will check and report back when i get more. but a peferred Suppliment for 1-IGF is Deer antler Velvet or Colostrum( make sure they have a fixed dosage of 1-IGF).
Sunset
(Login liquidSunset)
EVE MEMBERS
hmm..
March 17 2006, 10:17 PM
interesting, I never heard of that stuff. You can suppliment with deer antler velvet? Thats too cool
My hunny hunts deer...lolThanks for the info SugarQ! So you can buy those supplements of it at a health food store?
SugarQ
(Login SugarQ)
SENIOR MEMBER
Re: GABA may help women 30 and older who are doing NBE
March 17 2006, 10:22 PM
Some Extra sources linking NBE to 1-IGF (sorry its a lil long lol but helpful)
-----------------------------------------------------------------------------
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9098173&dopt=Abstract
"Breast size in relation to endogenous hormone levels, body constitution, and oral contraceptive use in healthy nulligravid women aged 19-25 years.
Jernstrom H, Olsson H.
Department of Oncology, University Hospital, Lund, Sweden.
In 1993 and 1994, the relation between breast size and hormonal factors and body constitution was studied in 65 healthy nulligravid women aged 19-25 years. Twenty-five women were current oral contraceptive users, 20 women were former users, and 20 women had never used oral contraceptives. Breast size was strongly positively correlated with current oral contraceptive use during menstrual cycle days 5-10, as well as days 18-23. No significant effect of former oral contraceptive use was seen on breast size. A significant increase in breast size between cycle days 5-10 and days 18-23 was seen among current oral contraceptive users. Breast size was significantly positively correlated with body mass index (weight (kg)/height (m)2), height, and weight in nonusers (i.e., former and never users combined) but not in current users. In nonusers, during the follicular phase, breast size was significantly positively associated with insulin-like growth factor 1. During the luteal phase, larger breast sizes were significantly associated with higher 17 beta-estradiol and progesterone levels and lower testosterone levels among nonusers. In models for current users, large breast sizes were significantly associated with high prolactin and luteinizing hormone levels and low follicle-stimulating hormone levels during cycle days 5-10. During cycle days 18-23, larger breast sizes correlated with low endogenous progesterone levels.
PMID: 9098173 [PubMed - indexed for MEDLINE] "
-----------------------------------------------------------------------------
http://www.endotext.org/male/male14/male14.htm
"ESTROGEN, GH AND IGF-1, PROGESTERONE, & PROLACTIN
Estrogen and progesterone act in an integrative fashion to stimulate normal adult female breast development. Estrogen, acting through its ER a receptor, promotes duct growth, while progesterone, also acting through its receptor (PR), supports alveolar development (15). This is demonstrated by experiments in ER a knockout mice which display grossly impaired ductal development, whereas the PR knockout mice possess significant ductal development, but lack alveolar differentiation (28,6).
Although estrogens and progestogens are vital to mammary growth, they are ineffective in the absence of anterior pituitary hormones (13). Thus, neither estrogen alone nor estrogen plus progesterone can sustain breast development without other mediators, such as GH and IGF-1, as confirmed by studies involving the administration of estrogen and GH to hypophysectomized and oophorectomized female rats, which resulted in breast ductal development. The GH effects on ductal growth are mediated through stimulation of IGF-1. This is demonstrated by studies of estrogen and GH administration to IGF-1 knockout rats that showed significantly decreased mammary development when compared to age-matched IGF-1- intact controls. Combined estrogen and IGF-1 treatment in these IGF-1 knockout rats restored mammary growth. (23, 40). In addition, Walden et al. demonstrated that GH-stimulated production of IGF-1 mRNA in the mammary gland itself, suggesting that IGF-1 production in the stromal compartment of the mammary gland acts locally to promote breast development (49). Furthermore, other data indicates that estrogen promotes GH secretion and increased GH levels, stimulating the production of IGF-1, which synergizes with estrogen to induce ductal development.
Like estrogen, progesterone has minimal effects in breast development without concomitant anterior pituitary hormones; again indicating that progesterone interacts closely with pituitary hormones. For example, prolonged treatment of dogs with progestogens such as depot medroxyprogesterone acetate or with proligestone caused increased GH and IGF-1 levels, suggesting that progesterone may also have an effect on GH secretion (33). In addition, clinical studies have correlated maximal cell proliferation to specific phases in the female menstrual cycle. For example, maximal proliferation occurs not during the follicular phase when estrogens reach peak levels and progesterone is low (less than 1 ng/mL [3.1nmol}), but rather, it occurs during the luteal phase when progesterone reaches levels of 10-20 ng/mL (31- 62nmol) and estrogen levels are two to three times lower than in the follicular phase (42). Furthermore, immunohistochemical studies of ER and PR showed that the highest percentage of proliferating cells, found almost exclusively in the type 1 lobules, contained the highest percentage of ER and PR positive cells (42). Similarly, there is immunocytological presence of ER, PR, and androgen receptors (AR) in gynecomastia and male breast carcinoma. ER, PR and AR expression was observed in 100% (30/30) of gynecomastia cases (41). Given these data and the fact that PR knockout mice lack alveolar development in breast tissue, it appears as if progesterone, analogous to estrogen, may increase GH secretion and act through its receptor on mammary tissue to enhance breast development, specifically alveolar differentiation (28, 18).
Prolactin is another anterior pituitary hormone integral to breast development. Prolactin is not only secreted by the pituitary gland but may be produced in normal mammary tissue epithelial cells and breast tumors. (44, 25). Prolactin stimulates epithelial cell proliferation only in the presence of estrogen and enhances lobulo-alveolar differentiation only with concomitant progesterone"
-----------------------------------------------------------------------------
"Hormonal breast augmentation: prognostic relevance of insulin-like growth factor-I.
Hartmann BW, Laml T, Kirchengast S, Albrecht AE, Huber JC.
Department of Senology, University of Vienna Medical School, Vienna, Austria.
Many women would like to alter their breasts but are deterred by the risks involved. Silicone breast implants have been linked to a variety of illnesses, the most controversial of which are connective-tissue diseases. These circumstances urged us to perform this pilot study using a non-invasive method that involved the application of 17 beta-estradiol as it is known that estradiol enhances expression of insulin-like growth factor-I (IGF-I) which can promote growth in breast tissue. Forty-five women were included in the study. Their breast volume, IGF-I, prolactin (PRL) and estradiol levels were measured before treatment and between each application of 80 mg estradiol polyphosphate. The women's satisfaction with the results obtained was also subsequently evaluated. In 21 women (46.7%), breast size increased from 824.3 +/- 13.7 mm to 898.5 +/- 12.5 mm after 6 months. In these women a significant increase in IGF-I values was noted after 4 weeks of treatment. The increase in IGF-I values was not statistically significant in the remaining women. In addition, treatment was not successful in these women. IGF-I concentration seems to be of prognostic value as far as the response of breast tissue to estrogen stimulation is concerned. If IGF-I levels do not increase within 1 month, treatment should be discontinued. If IGF-I values do increase, this indicates that treatment is likely to be successful and can therefore be continued.
PMID: 9610425 [PubMed - indexed for MEDLINE]
Logged"
SugarQ
(Login SugarQ)
SENIOR MEMBER
Re: GABA may help women 30 and older who are doing NBE
March 17 2006, 10:28 PM
Important info about IGF suplimentation came from Fawnmarie
she said:
"Collostrum is an immune stimulant, but the best way to increase IGF is to understand how it's produced and take advantage of it.
IGF is produced in the liver from HGH. HGH is produced:
1) during the first 90 mintues of sleep
2) during intense exercise
3) when hungry
Things that suppress HGH production are:
1) sleeping on a "full" stomach
2) heavy sugar and starches
3) not waiting an adequate amount of time between meals.
After optimizing HGH production, then you need to turn attention to the liver, where IGF is made:
1) keep the liver clean (use liver cleanses)
2) eat an adequate amount of animal protein daily
3) avoid large amounts of alcohol on a regular basis
4) eat plenty of live, raw vegetables and fruits - apples and carrots are particularly good for the liver
If you are over 30-35, then you may want to consider supplements that increase HGH production - however be advised that they can increase the risk of cancer if it runs in your family or you have other risk factors.
Some supplements might include GABA, l'arginine or l'ornithine before bed (on an empty stomach). Be advised that GABA, in a small percentage of the population can cause physical side effects which are temporary, but mimic those of a full out anxiety attack (heart palpitations, flushing face, racing mind), and l'arginine can increase sensitivity in those with chronic pain conditions.
Fawn"
you can buy dear velvent and collustrum in any most health foods but you need to make sure that the IGF content is listed. a prefered brand is "NOW" IGF spray or losange but there are many others.
Sunset
(Login liquidSunset)
EVE MEMBERS
WOW
March 17 2006, 10:51 PM
Thanks SugarQ that is really interesting thANK YOU SO MUCH!
Sounds like it would be better than GABA, and did you see that she said GABA can cause permanet damage? I had no clue thank you! I am sure more ladies will find your info informative and interesting!
Sunset
(Login liquidSunset)
EVE MEMBERS
oops
March 17 2006, 10:52 PM
She said GABA side effects are temporary NOT permanant. But they mimic a heart attach?! Sounds no good
SugarQ
(Login SugarQ)
SENIOR MEMBER
yeah i recall reading that in her book
March 17 2006, 10:58 PM
I think i should check to see if 1-IGF suppliments have any negative effect too. im going to start looking.
Sunset
(Login liquidSunset)
EVE MEMBERS
ok
March 17 2006, 11:04 PM
thats always a good idea, thank you SugarQ.