06-02-2016, 16:25
BCP and progesterone
October 11 2007 at 12:04 PM Louise (Login Louise1982)
SENIOR MEMBER
This is the response to a question I asked a medical site about progesterone in BCP as I switched brands and noticed there was a large increase in dose of the progesterone component so I wanted to know if it was more progestoronic overall or if the new drug is weaker hence you need more of it:
"You recently asked the NLH Q&A service regarding whether the combined oral contraceptive Dianette (containing 2 mg of the progesterone cyproterone) is more progestogenic than Microgynon (containing 0.15 mg of levonogestrel) and which would be more suitable for women with low circulating progesterone. I am responding to your question as it was referred to London medicines information.
Cyproterone is a progesterone but also has anti-androgenic properties and is therefore preferred for women with acne, oily skin, or hirsutism. Levonorgestrel is also a progesterone but without apparent anti-androgenic activity. As such, whilst both cyproterone and levonorgestrel are potent progesterones a direct comparison in terms of equivalent doses is not available. It is also worth considering that interindividual pharmacokinetic and physiological variation may occur, resulting in 10 fold differences in circulating progesterone in women taking the same formulation of the same pill and sampled at the same time. Such variation is further compounded by differences in target organ sensitivity. Taking this into account it seems suggesting a specific suitable progesterone for a women with low circulating progesterone could only be achieved on an individual basis and may require specialist input."
So it seems that again it is down to our own individual bodies to make use of the BCP (or not!) and it is pretty much down to luck and genetics whether it helps boob growth or hormonal symptoms.
Melissa
(no login)
Re: BCP and progesterone
October 16 2007, 8:44 PM
Wow the effect can vary so much from one person to another and hormone levels can be so different. No wonder we need a forum like this to examine all these things. It seems hopeless trying to find general answers!
Andrea
(no login)
Re: BCP and progesterone
October 19 2007, 6:37 PM
I'm not convinced that BCP for breast growth is the way to go. I got some increase when on BCP, but it must have been only swelling, as it disppeared immediately I came off the pill.
October 11 2007 at 12:04 PM Louise (Login Louise1982)
SENIOR MEMBER
This is the response to a question I asked a medical site about progesterone in BCP as I switched brands and noticed there was a large increase in dose of the progesterone component so I wanted to know if it was more progestoronic overall or if the new drug is weaker hence you need more of it:
"You recently asked the NLH Q&A service regarding whether the combined oral contraceptive Dianette (containing 2 mg of the progesterone cyproterone) is more progestogenic than Microgynon (containing 0.15 mg of levonogestrel) and which would be more suitable for women with low circulating progesterone. I am responding to your question as it was referred to London medicines information.
Cyproterone is a progesterone but also has anti-androgenic properties and is therefore preferred for women with acne, oily skin, or hirsutism. Levonorgestrel is also a progesterone but without apparent anti-androgenic activity. As such, whilst both cyproterone and levonorgestrel are potent progesterones a direct comparison in terms of equivalent doses is not available. It is also worth considering that interindividual pharmacokinetic and physiological variation may occur, resulting in 10 fold differences in circulating progesterone in women taking the same formulation of the same pill and sampled at the same time. Such variation is further compounded by differences in target organ sensitivity. Taking this into account it seems suggesting a specific suitable progesterone for a women with low circulating progesterone could only be achieved on an individual basis and may require specialist input."
So it seems that again it is down to our own individual bodies to make use of the BCP (or not!) and it is pretty much down to luck and genetics whether it helps boob growth or hormonal symptoms.
Melissa
(no login)
Re: BCP and progesterone
October 16 2007, 8:44 PM
Wow the effect can vary so much from one person to another and hormone levels can be so different. No wonder we need a forum like this to examine all these things. It seems hopeless trying to find general answers!
Andrea
(no login)
Re: BCP and progesterone
October 19 2007, 6:37 PM
I'm not convinced that BCP for breast growth is the way to go. I got some increase when on BCP, but it must have been only swelling, as it disppeared immediately I came off the pill.