09-07-2016, 19:59
Androgens stand in the way, but there's an exception.
Too much estrogens aren't healthy. Too much unbound estrogens, or any other hormone for that matter, do desensitize it's receptor. They may be effective at first, but they immediately lose their effectiveness due to that overload that desensitized the receptor.
Hormones bound to SHBG usually don't react, and SHBG usually binds to many excessive estrogens or androgens.
Too much estrogens aren't healthy. Too much unbound estrogens, or any other hormone for that matter, do desensitize it's receptor. They may be effective at first, but they immediately lose their effectiveness due to that overload that desensitized the receptor.
Hormones bound to SHBG usually don't react, and SHBG usually binds to many excessive estrogens or androgens.