25-01-2012, 20:41
Hi Susan,
The body metabolizes estrone to 16α-hydroxyestrone and to 2-hydroxyestrone. Neither of them is estrogenic, that's what I mean by "useless". This also means your body has to make estrogens continually to make up for the loss.
WY blocks the way to 16α-hydroxyestrone. So you lose estrogens slower. I agree WY is a good one for peri-menopause, because hormones can go up or down fast at this time, and WY, like licorice, affects all four main NBE hormones: the diosgenin increases progesterone and prolactin, the β-sitosterol is an anti-androgen, and estrogens increase because estrone is not broken down to 16α-hydroxyestrone.
The body metabolizes estrone to 16α-hydroxyestrone and to 2-hydroxyestrone. Neither of them is estrogenic, that's what I mean by "useless". This also means your body has to make estrogens continually to make up for the loss.
WY blocks the way to 16α-hydroxyestrone. So you lose estrogens slower. I agree WY is a good one for peri-menopause, because hormones can go up or down fast at this time, and WY, like licorice, affects all four main NBE hormones: the diosgenin increases progesterone and prolactin, the β-sitosterol is an anti-androgen, and estrogens increase because estrone is not broken down to 16α-hydroxyestrone.