24-03-2012, 15:06
(This post was last modified: 24-03-2012, 15:29 by mochaccino.)
I want to start a new program that involves cycling bioidentical estradiol and progesterone creams. I might also include something to block shbg. I'm gonna try to explain some of my reasons for trying this approach, mostly in the hope that someone will correct me if i'm wrong or elaborate on some of these ideas. Okay, here goes nothing...
There used to be a lot of talk about how some phytoestrogens are even more estrogenic then estradiol. I think I even remember someone claiming that deoxymiroestrol was hundreds of times stronger than endogenous estrogens. I looked into it and came to the conclusion that, lucky for us, the estrogenic potential of all the major phytoestrogens have been studied, and although the different studies are not all directly comparable to eachother, every real endocronologist seems to believe that there are absolutely no phytoestrogens, including deoxymiroestrol, that are as estrogenic as estradiol. I could have completely misinterpreted what was being said, but I don't see how I could have. They all seem pretty straight forward on this point. I definitely welcome correction on this issue, if anyone has some contradictory info. Unfortunately, this probably also means that bioidentical estradiol is a lot more dangerous than most phytoestrogens, in the sense that it would be a lot easier to take too much. If I do decide to use it, I'll probably need to do saliva tests at least once a month.
Another issue I've been thinking about is that the number one most important goal of almost any hormonal program is stimulating the estrogen receptors in the breasts as much as possible without triggering too much down-regulation. In the beginning, I just could not figure out why some herbal programs were so complicated, including the one I eventually ended up following. Theoretically it should be possible to stimulate the estrogen receptors in the breasts locally with some sort of estrogen, or estrogen mimic, and that should be enough for growth. In real life, estrogen has to be balanced by progesterone to avoid serious health problems, but one of the primary functions of progesterone is to halt the proliferation of estrogen sensitive cells, so I think it would probably be best to apply progesterone everywhere EXCEPT my breasts. Does this make sense? Some people have had success constantly applying PC, but it can cause swelling indirectly by increasing prolactin and filling up the milk ducts, and can also directly cause edema (water storage) in all the breast tissues. PC also causes real growth of mammary glands but not fat, so rhe few people who have had permanent growth on PC have probably had an usually huge amount of growth of mammary glands. Then again, it's also possible for progesterone to be converted to estrogen in the body, and in some people this conversion may be much more efficient then in others. Of course, there are plenty of people who take it just to balance estrogen, and that's why I'll be taking it. It also up-regulates estrogen receptors, as an added bonus. How should I go about balancing these hormones throughout my cycle? I have no idea. So confused
There used to be a lot of talk about how some phytoestrogens are even more estrogenic then estradiol. I think I even remember someone claiming that deoxymiroestrol was hundreds of times stronger than endogenous estrogens. I looked into it and came to the conclusion that, lucky for us, the estrogenic potential of all the major phytoestrogens have been studied, and although the different studies are not all directly comparable to eachother, every real endocronologist seems to believe that there are absolutely no phytoestrogens, including deoxymiroestrol, that are as estrogenic as estradiol. I could have completely misinterpreted what was being said, but I don't see how I could have. They all seem pretty straight forward on this point. I definitely welcome correction on this issue, if anyone has some contradictory info. Unfortunately, this probably also means that bioidentical estradiol is a lot more dangerous than most phytoestrogens, in the sense that it would be a lot easier to take too much. If I do decide to use it, I'll probably need to do saliva tests at least once a month.
Another issue I've been thinking about is that the number one most important goal of almost any hormonal program is stimulating the estrogen receptors in the breasts as much as possible without triggering too much down-regulation. In the beginning, I just could not figure out why some herbal programs were so complicated, including the one I eventually ended up following. Theoretically it should be possible to stimulate the estrogen receptors in the breasts locally with some sort of estrogen, or estrogen mimic, and that should be enough for growth. In real life, estrogen has to be balanced by progesterone to avoid serious health problems, but one of the primary functions of progesterone is to halt the proliferation of estrogen sensitive cells, so I think it would probably be best to apply progesterone everywhere EXCEPT my breasts. Does this make sense? Some people have had success constantly applying PC, but it can cause swelling indirectly by increasing prolactin and filling up the milk ducts, and can also directly cause edema (water storage) in all the breast tissues. PC also causes real growth of mammary glands but not fat, so rhe few people who have had permanent growth on PC have probably had an usually huge amount of growth of mammary glands. Then again, it's also possible for progesterone to be converted to estrogen in the body, and in some people this conversion may be much more efficient then in others. Of course, there are plenty of people who take it just to balance estrogen, and that's why I'll be taking it. It also up-regulates estrogen receptors, as an added bonus. How should I go about balancing these hormones throughout my cycle? I have no idea. So confused