09-12-2012, 15:20
Guggul, does have an effect on hormones, so if you are mixing it yourself at higher dosage and using it daily, you may see some effects from that.
"Daily recommendations for the purified guggul extract are typically based on the amount of guggulsterones in the extract. A common intake of guggulsterones is 25 mg three times per day. Most extracts contain 2.5–5% guggulsterones and can be taken daily for lowering high cholesterol and/or triglycerides."
"Guggulsterone behaved as antagonists of androgen, glucocorticoid, and MR, but as agonists of
progesterone receptors. Agonist activity was also demonstrated with estrogen receptor (ER) alpha;
however, the potency was very low (EC50 > 5000 nM). In addition, GS displayed activity in functional
assays in cell lines expressing endogenous androgen, glucocorticoid, estrogen receptor, and
progesterone receptors. These data suggest that the variety of pharmacological effects exhibited by GS
may be mediated by targeting several steroid receptors.
"
Commipheroline - It up-regulates the lipogenic enzyme G3PDH (+215%) to enhance triglyceride storage in adipocytes. Commipheroline inhibits fat breakdown by limiting cAMP production
I wonder why the effects of lipofilling would only be temporary?....hmm maybe I will start testing mine out on my eye wrinkles.
"Daily recommendations for the purified guggul extract are typically based on the amount of guggulsterones in the extract. A common intake of guggulsterones is 25 mg three times per day. Most extracts contain 2.5–5% guggulsterones and can be taken daily for lowering high cholesterol and/or triglycerides."
"Guggulsterone behaved as antagonists of androgen, glucocorticoid, and MR, but as agonists of
progesterone receptors. Agonist activity was also demonstrated with estrogen receptor (ER) alpha;
however, the potency was very low (EC50 > 5000 nM). In addition, GS displayed activity in functional
assays in cell lines expressing endogenous androgen, glucocorticoid, estrogen receptor, and
progesterone receptors. These data suggest that the variety of pharmacological effects exhibited by GS
may be mediated by targeting several steroid receptors.
"
Commipheroline - It up-regulates the lipogenic enzyme G3PDH (+215%) to enhance triglyceride storage in adipocytes. Commipheroline inhibits fat breakdown by limiting cAMP production
I wonder why the effects of lipofilling would only be temporary?....hmm maybe I will start testing mine out on my eye wrinkles.