[lora]

i will put this very important information in my plan,


Improve Estrogen Metabolism By Promoting the C-2 Pathway
Promoting the C-2 pathway of estrogen metabolism is probably the most important thing you can do to prevent cancer. The first step of estrogen elimination is for enzymes to initiate metabolism by joining the estrogen molecule. This will happen at either the 2-carbon position or the 16-carbon position of the molecule, which determines the pathway the estrogen will head down.

The C-2 pathway produces very weak estrogenic activity and is termed “good” estrogen. In contrast, the C-16 pathway produces robust estrogenic activity and promotes tissue damage that leads to cancer. There’s also a C-4 pathway, that is not good, but its role is small and for simplicity sake you only need to know that you want to avoid it as well.


so,

Key nutrients for supporting the C-2 pathway are EPA fish oils, phytoestrogens, and of special importance, B vitamins and a substance called DIM. The B vitamins, particularly B6, B12, and folic acid promote the C-2 pathway. B6 is also known to decrease gene activity once estrogen is bound to a receptor, meaning this vitamin can inhibit cell damage and cancer development.

DIM is a compound found in cruciferous vegetables such as broccoli and cauliflower. It is often taken in supplement form because you would need to eat large quantities of these vegetables daily in order to provide sufficient DIM to have an effect on estrogen elimination.

Take note that most people need to supplement with a B vitamin and that trainees who take BCAAs will quickly become deficient in B vitamins, making it essential that you get extra. A high protein diet that provides adequate BCAA levels also requires extra B vitamins.