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Side effects of NBE supplements

#41

(17-01-2014, 10:51)Rihana Wrote:  From my experience: Side effects are from doses that are too high. Taking too high doses in the beginning stops growth too.
PM should never be used throughout the cycle, otherwise It will mess up cycle.
Follicular phase Or first 15 days are Ok for PM, if you want a regular period.
Before starting any nbe routine, It's always best to test hormones level so that you may choose herbs accordingly.
Usually I've seen women copying others routines, which is not at all good because everyone is different!

I'm menopausal & have no periods. How would I cycle? Should I just pick a day in the month & pretend I'm menstruating or should I not worry about cycling & take PM all the time?
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#42

(15-01-2014, 18:38)Lotus~Aphrodité Wrote:  Thyroid and phytoestrogens,

Although the first link is lengthy, the attachment posted states how the thyroid is effected from phyto's.

Understanding how phytoestrogens (soy) effects your thyroid is well documented, just do a basic search and you'll see. Please know the difference about fermented soy and the age old theory about Asian cultures. http://www.optimumchoices.com/Soy.htm


http://www.slideshare.net/roger961/chapt...thyroiddoc
http://www.ncbi.nlm.nih.gov/pubmed/21325465
http://thyroid.about.com/cs/soyinfo/a/soy_2.htm

Good work Lotus.
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#43

(13-01-2014, 17:43)Lotus~Aphrodité Wrote:  
(13-01-2014, 08:09)danim Wrote:  Well, I´m confused now. Does SP decrease estrogen ? That is new to me.

It's just possible interactions. Wink

" According to Jaroslav Drsata, a scientist in the Czech Republic, the enzyme-blocking properties of saw palmetto may include aromatase ".
If this is true, Shouldn´t SP be better as anti-androgen for the girls with estrogen dominance ? after all spearmint reduces testosterone but also increases estrogen.
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#44

(23-01-2014, 12:03)Ceci82 Wrote:  
(13-01-2014, 17:43)Lotus~Aphrodité Wrote:  
(13-01-2014, 08:09)danim Wrote:  Well, I´m confused now. Does SP decrease estrogen ? That is new to me.

It's just possible interactions. Wink

" According to Jaroslav Drsata, a scientist in the Czech Republic, the enzyme-blocking properties of saw palmetto may include aromatase ".
If this is true, Shouldn´t SP be better as anti-androgen for the girls with estrogen dominance ? after all spearmint reduces testosterone but also increases estrogen.
Hi Cecil, sorry for the info overload.

When searching for SP you come up with wide range of opinions and studies and mostly with the same methodologies. Below it's listed an interaction when taking with estrogen pills.

Saw palmetto seems to decrease estrogen levels in the body. Taking saw palmetto
along with estrogen pills might decrease the effectiveness of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.

http://www.nlm.nih.gov/medlineplus/drugi...l/971.html
http://www.lef.org/magazine/mag2007/jan2007_aas_01.htm
And of that:
Maintaining endogenous testosterone (T) levels as men age may slow the symptoms of sarcopenia, andropause and decline in physical performance. Drugs inhibiting the enzyme 5alpha-reductase (5AR) produce increased blood levels of T and decreased levels of dihydrotestosterone (DHT). However, symptoms of gynecomastia have been reported due to the aromatase (AER) enzyme converting excess T to estradiol (ES)
http://www.greenmedinfo.com/pharmacologi...inhibitors

Searching for SP within our forum I came across this post from chrishoney, who is a medical professional who's opinion I trust and respect!
(04-03-2012, 20:33)chrishoney Wrote:  I find the linked article you posted, VERY misleading. I tried going through the sources/references listed at the end of the article and the only one I could find that mentioned an antiestrogenic effect of SP was referring specifically to prostatic tissue.

The article itself also says that SP is likely ineffective in treating BPH but if you dig into the research, it turns out there is NO standard way of producing/extracting SP into capsules so comparing one brand to another or even production lots within a single brand is impossible. There is too much variance in the amount/strength of the likely active component of SP (lipidic liposterols). There is a company in the EU that prepares a standardized preparation lipidic liposterols derived from SP and the evidence shows it has significant effect on BPH symptoms (Permixon, Pierre Fabre Médicament, Castres, France).

Doing a search on "antiestrogenic effects of saw palmetto" on scholar.google.com yields similar results. The anti-estrogenic activity has been noted in prostatic tissue, not "in the body" as stated in several places in the article. To further complicate things, SP apparently has both anti-androgenic AND anti-estrogenic effects experimentally.

My personal experience is that PM worked just fine without the use of SP. I can't say that SP had NO effect or that it opposed PM, just that PM alone, worked fine.



Concerning the Czech scientist I couldn't find when his research was done, but his theory does raise the question for more debate. We need to open our minds up to the possibility of new information when it comes to NBE. Some see it as a nuisance and shouldn't be entertained for discussion, that's ok!. If you're getting results with your NBE great, don't mess with it, but between you and me I'd like to make sure that I didn't leave more than a B-cup on the table. So if there's new studies, research that might be working for somebody else I'd like to know!. Ideally, providing two sides to each theory is best for our purposes in regards for NBE.

Quote:Just done some digging, it seems out of all the teas peppermint has the strongest estrogenic increasing and testosterone decreasing activity.
“Among them, the extract of peppermint tea exhibited the highest estrogenic activity.”
http://www.springerlink.com/content/12l57414p3035173/

“After five days, the women’s levels of free testosterone (the biologically active form) declined, although their total testosterone level stayed the same. Women’s levels of luteinizing hormone, follicle stimulating hormone, and estrogen rose, while their triglyceride levels dropped significantly…The researchers found a significant decrease in free (active) testosterone in the blood and an increase in several female hormones including follicle-stimulating hormone.”
http://news.bbc.co.uk/1/hi/health/6376599.stm
(Note: this doesn’t mean the above study would necessarily have the same effect in men)
“After treatment with spearmint teas, there was a significant decrease in free testosterone and increase in luteinizing hormone, follicle-stimulating hormone and estradiol.”
http://www.ncbi.nlm.nih.gov/pubmed/17310...stractPlus
http://www.healthyfellow.com/290/mint-te...omment-949
Of spearmint and peppermint, peppermint is higher in estrogenic properties
http://www.zhion.com/herb/Peppermint.html
http://www.breastnexus.com/showthread.php?tid=15674
http://www.livestrong.com/article/412385...tagonists/

Take care Ceci, Wink btw, have you heard of this? (it is important to know that only 5% of testosterone is transformed into DHT.)
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#45

Ceci,

I have another example for you to consider- at least what I believed happened to me!
Quote:Lakshman KM, Kaplan B, Travison TG, et al. The Effects of Injected Testosterone Dose and Age on the Conversion of Testosterone to Estradiol and Dihydrotestosterone in Young and Older Men. J Clin Endocrinol Metab:jc.2010-0102.

Background: During testosterone (T) therapy, T is partly converted to 17{beta}-estradiol (E2) and 5{alpha}-dihydrotestosterone (DHT). Effects of age, testosterone dose, and body composition on total and free E2 and DHT levels are unknown.

Objective: We evaluated age and dose-related differences in E2 and DHT levels in response to graded doses of testosterone enanthate in young and older men.

Methods: Fifty-one young (aged 19-35 yr) and 52 older (aged 59-75 yr) men completed treatment with monthly injections of a GnRH agonist plus randomly assigned weekly doses of testosterone enanthate (25, 50, 125, 300, or 600 mg) for 5 months.

Results: During testosterone administration, total and free E2 levels increased dose-dependently (dose effect, P < 0.001) in both young and older men. Total and free E2 levels and E2:T ratios during T administration were higher in older than young men, but age-related differences in free E2 and free E2:T ratios were not significant after adjusting for testosterone levels, percentage fat mass, and SHBG. DHT levels and DHT:T ratios were dose-related but did not differ between young and older men. Mechanistic modeling of free hormone data revealed that the conversions of T to E2 and DHT were both consistent with saturable Michaelis-Menten kinetics. The in vivo Km values were estimated to be 1.83 nM for aromatase and 3.35 nM for 5{alpha}-reductase, independent of age. The Vmax parameter for E2 was 40% higher in older men than younger men, but Vmax for DHT was not significantly different between age groups.

Conclusions: During im testosterone administration, E2 and DHT levels exhibit saturable increases with dose. The rate of whole body aromatization is higher in older men, partly related to their higher percentage fat mass, SHBG, and testosterone levels.

http://thinksteroids.com/forum/mens-heal...94117.html

So basically because of my fat ass!......when I was on T therapy it created a perfect storm so to speak for me in terms of breast growth!
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#46

I was taking Spearmint ( And I was having success) then I changed for sp and my growth stalled. Now I´m back to Spearmint -after a break -and my growth has returned.

I think SP turn ineffective PM. ( At least in my case).

btw Lotus : Impressive researcher skills ! Smile
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#47

Dumb question: is the spearment a pill, extract or tea? Is it taken internally or topical?
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#48

(28-01-2014, 14:15)lostacres6 Wrote:  Dumb question: is the spearment a pill, extract or tea? Is it taken internally or topical?

you can get pill or tea taken internally .
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#49

Great thread Lotus...this should be a sticky!
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#50

(28-01-2014, 16:36)myboobs Wrote:  
(28-01-2014, 14:15)lostacres6 Wrote:  Dumb question: is the spearment a pill, extract or tea? Is it taken internally or topical?

you can get pill or tea taken internally .

Exactly
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