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Glutamic Acid in Protein Powders - risk for cancer..?

#1
Exclamation 

So for the past two years Ive been watching "the truth about cancer" documentaries and both years theyve dedicated some research to "glutamic acid and/or glutamine" in the role of developing cancer.

This of course is very high in Protein powders and certain foods of course.

My new protein powder has a HUGE amount of glutamic acid per serving and im reluctant to use the stuff.

What do you guys think? Anyone care to research into this for me?

Further to this ive been reserching theres NO therapeutic value to taking isolated amino acids and lets face it we all are doing THAT or supplementing with protein powders.

Keen to hear your thoughts.
Thanks
Reply
#2

(02-05-2016, 21:07)ellacraig Wrote:  So for the past two years Ive been watching "the truth about cancer" documentaries and both years theyve dedicated some research to "glutamic acid and/or glutamine" in the role of developing cancer.

This of course is very high in Protein powders and certain foods of course.

My new protein powder has a HUGE amount of glutamic acid per serving and im reluctant to use the stuff.

What do you guys think? Anyone care to research into this for me?

Further to this ive been reserching theres NO therapeutic value to taking isolated amino acids and lets face it we all are doing THAT or supplementing with protein powders.

Keen to hear your thoughts.
Thanks

guess I will have to toss out my Bragg's liquid amino's then Sad though they are good for that umami taste in your food...
Reply
#3

(02-05-2016, 21:07)ellacraig Wrote:  So for the past two years Ive been watching "the truth about cancer" documentaries and both years theyve dedicated some research to "glutamic acid and/or glutamine" in the role of developing cancer.

This of course is very high in Protein powders and certain foods of course.

My new protein powder has a HUGE amount of glutamic acid per serving and im reluctant to use the stuff.

What do you guys think? Anyone care to research into this for me?

The main problem as I understand it is something you touch upon later in your post yourself, I'll discuss more at length there.

(02-05-2016, 21:07)ellacraig Wrote:  Further to this ive been reserching theres NO therapeutic value to taking isolated amino acids and lets face it we all are doing THAT or supplementing with protein powders.

THIS is where glutamic acid and especially its isolated and rearranged form glutamate cause problems. First, glutamic acid is not even a required acid, our body synthesizes what we NEED on its own if there isn't enough present. Second, when taken as an isolated acid, THEN it can add to cancer risk because our body WON'T flush out excess, which then through various metabolic processes, can become some nasty stuff. This happens even quicker to the glutamate form than the natural glutamic acid. Our bodies can't even use the glutamate form.

(02-05-2016, 21:07)ellacraig Wrote:  Keen to hear your thoughts.
Thanks

Your protein powder is probably fine, all it is is a refined product where the only "refinement" is stripping it of as many non-protein components from the original source food as possible though low-impact methods. It's still a "natural" product, the most they do to it is some cooking, maybe some fermenting, depending on source food. Soy proteins must be fermented. Milk proteins are only cooked and centrifuged and filtered. After fermentation soy is cooked further, centrifuged and filtered. Not sure how they do pea or hemp etc proteins.

While there will be glutamic acid in ANY protein source, that shit's in literally every food, any good quality controlled protein powder will NOT have the altered form glutamate. It's also not an isolated protein, it has other proteins with it.

The real question is, how much protein do you actually need to be eating? Do you actually need to supplement it? Or would you be best off just getting it from meats, fish, and animal biproduct. I know you're on a sibo diet, so you do need to avoid plant protein, because it comes packed with a ton of sugars, even when refined.
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#4

(03-05-2016, 00:13)Tanya Marie Squirrel Wrote:  
(02-05-2016, 21:07)ellacraig Wrote:  So for the past two years Ive been watching "the truth about cancer" documentaries and both years theyve dedicated some research to "glutamic acid and/or glutamine" in the role of developing cancer.

This of course is very high in Protein powders and certain foods of course.

My new protein powder has a HUGE amount of glutamic acid per serving and im reluctant to use the stuff.

What do you guys think? Anyone care to research into this for me?

Further to this ive been reserching theres NO therapeutic value to taking isolated amino acids and lets face it we all are doing THAT or supplementing with protein powders.

Keen to hear your thoughts.
Thanks

guess I will have to toss out my Bragg's liquid amino's then Sad though they are good for that umami taste in your food...

The only one in really aware is bad is glutamic acid. If the levels are low in your Braggs I wouldn't be concerned cause your Gina get it from diet anyway . It's just the real strong sources ie protein powders that freaks me out. Ie my latest protein powder has 313 MG PER SERVE and they suggest 2 servings a flippin day..
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#5

Proteins and peptides don't carry the risks of free amino acids, except those rich in leucine. Whey is rich in leucine and it increases mTOR signalling just like leucine does. In the short run you get more growth, but in the long run your stem cells grow resistant and stop dividing. mTOR inhibitors increase animal lifespan.

Cysteine interferes with nitric oxide signalling. Glutamine is great food for an injured gut, but it converts to arginine, arginine increases growth hormone release, and consistently-high growth hormone will shorten lifespan. (Intermittent cycles every few months might be OK to make sure you get needed maintenance done.) Glutamate and glutamic acid are the same thing, they convert between each other by acid-base chemistry. At the body's pH it's glutamate, and taking it as free amino acid will increase risk of metabolic syndrome. They have a term called "monosodium L-glutamate (MSG)-induced obese rats". If you have a leaky blood-brain barrier from inflammation you might get neurological symptoms from it because glutamate is an excitatory neurotransmitter.

Proteins and peptides are only chopped into amino acids as needed, so free amino acid levels are kept under control as long as you don't deliberately take them.
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#6

Thanks heaps Abi and Candace, having brain fog right now (another sibo goodie) but will scrutinise your responses. As for sibo yeh my fear was/is when they try heal my gut they'll likely have me taking mega doses of glutamine to heal leaky gut. I know the msg link is very bad, wasn't sure if that crossed over into protein powders as well. The cancer Drs were against glutamine use .
Maybe a good WHEY not plant based protein may in order shirt term to help with strength . But yeh I'm running off on a tangent , will thoroughly read your responses.
Thank you so much.
Reply
#7

(03-05-2016, 00:21)AbiDrew85 Wrote:  
(02-05-2016, 21:07)ellacraig Wrote:  So for the past two years Ive been watching "the truth about cancer" documentaries and both years theyve dedicated some research to "glutamic acid and/or glutamine" in the role of developing cancer.

This of course is very high in Protein powders and certain foods of course.

My new protein powder has a HUGE amount of glutamic acid per serving and im reluctant to use the stuff.

What do you guys think? Anyone care to research into this for me?

The main problem as I understand it is something you touch upon later in your post yourself, I'll discuss more at length there.

(02-05-2016, 21:07)ellacraig Wrote:  Further to this ive been reserching theres NO therapeutic value to taking isolated amino acids and lets face it we all are doing THAT or supplementing with protein powders.

THIS is where glutamic acid and especially its isolated and rearranged form glutamate cause problems. First, glutamic acid is not even a required acid, our body synthesizes what we NEED on its own if there isn't enough present. Second, when taken as an isolated acid, THEN it can add to cancer risk because our body WON'T flush out excess, which then through various metabolic processes, can become some nasty stuff. This happens even quicker to the glutamate form than the natural glutamic acid. Our bodies can't even use the glutamate form.

(02-05-2016, 21:07)ellacraig Wrote:  Keen to hear your thoughts.
Thanks

Your protein powder is probably fine, all it is is a refined product where the only "refinement" is stripping it of as many non-protein components from the original source food as possible though low-impact methods. It's still a "natural" product, the most they do to it is some cooking, maybe some fermenting, depending on source food. Soy proteins must be fermented. Milk proteins are only cooked and centrifuged and filtered. After fermentation soy is cooked further, centrifuged and filtered. Not sure how they do pea or hemp etc proteins.

While there will be glutamic acid in ANY protein source, that shit's in literally every food, any good quality controlled protein powder will NOT have the altered form glutamate. It's also not an isolated protein, it has other proteins with it.

The real question is, how much protein do you actually need to be eating? Do you actually need to supplement it? Or would you be best off just getting it from meats, fish, and animal biproduct. I know you're on a sibo diet, so you do need to avoid plant protein, because it comes packed with a ton of sugars, even when refined.

OKAY ABI CANDACE AND LOTUS

CAN YOU TELL ME about "antigens" in whey protein??

I've heard whey is unsuitable for human consumption and anti Genesis with whey?...

Sorry to bombard you. My issue being my OVERALL food intake is restricted soo much I'm trying to find a suitable protein source something to with low amino acids is bad for my condition.

Thank you x
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#8

It's a good thing:

https://www.ncbi.nlm.nih.gov/pubmed/12639817

Basically, it boosts your resistance to disease.
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#9

This is interesting: mTOR is connected to the immune response to milk.

Neuropharmacology. 2015 Oct;97:220-32.
mTOR plays an important role in cow's milk allergy-associated behavioral and immunological deficits.
Wu J, de Theije CG, da Silva SL, van der Horst H, Reinders MT, Broersen LM, Willemsen LE, Kas MJ, Garssen J, Kraneveld AD.

Abstract

Autism spectrum disorder (ASD) is multifactorial, with both genetic as well as environmental factors working in concert to develop the autistic phenotype. Immunological disturbances in autistic individuals have been reported and a role for food allergy has been suggested in ASD. Single gene mutations in mammalian target of rapamycin (mTOR) signaling pathway are associated with the development of ASD and enhanced mTOR signaling plays a central role in directing immune responses towards allergy as well. Therefore, the mTOR pathway may be a pivotal link between the immune disturbances and behavioral deficits observed in ASD. In this study it was investigated whether the mTOR pathway plays a role in food allergy-induced behavioral and immunological deficits. Mice were orally sensitized and challenged with whey protein. Meanwhile, cow's milk allergic (CMA) mice received daily treatment of rapamycin. The validity of the CMA model was confirmed by showing increased allergic immune responses. CMA mice showed reduced social interaction and increased repetitive self-grooming behavior. Enhanced mTORC1 activity was found in the brain and ileum of CMA mice. Inhibition of mTORC1 activity by rapamycin improved the behavioral and immunological deficits of CMA mice. This effect was associated with increase of Treg associated transcription factors in the ileum of CMA mice. These findings indicate that mTOR activation may be central to both the intestinal, immunological, and psychiatric ASD-like symptoms seen in CMA mice. It remains to be investigated whether mTOR can be seen as a therapeutic target in cow's milk allergic children suffering from ASD-like symptoms.
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#10

(06-05-2016, 02:54)Candace Wrote:  This is interesting: mTOR is connected to the immune response to milk.

Neuropharmacology. 2015 Oct;97:220-32.
mTOR plays an important role in cow's milk allergy-associated behavioral and immunological deficits.
Wu J, de Theije CG, da Silva SL, van der Horst H, Reinders MT, Broersen LM, Willemsen LE, Kas MJ, Garssen J, Kraneveld AD.

Abstract

Autism spectrum disorder (ASD) is multifactorial, with both genetic as well as environmental factors working in concert to develop the autistic phenotype. Immunological disturbances in autistic individuals have been reported and a role for food allergy has been suggested in ASD. Single gene mutations in mammalian target of rapamycin (mTOR) signaling pathway are associated with the development of ASD and enhanced mTOR signaling plays a central role in directing immune responses towards allergy as well. Therefore, the mTOR pathway may be a pivotal link between the immune disturbances and behavioral deficits observed in ASD. In this study it was investigated whether the mTOR pathway plays a role in food allergy-induced behavioral and immunological deficits. Mice were orally sensitized and challenged with whey protein. Meanwhile, cow's milk allergic (CMA) mice received daily treatment of rapamycin. The validity of the CMA model was confirmed by showing increased allergic immune responses. CMA mice showed reduced social interaction and increased repetitive self-grooming behavior. Enhanced mTORC1 activity was found in the brain and ileum of CMA mice. Inhibition of mTORC1 activity by rapamycin improved the behavioral and immunological deficits of CMA mice. This effect was associated with increase of Treg associated transcription factors in the ileum of CMA mice. These findings indicate that mTOR activation may be central to both the intestinal, immunological, and psychiatric ASD-like symptoms seen in CMA mice. It remains to be investigated whether mTOR can be seen as a therapeutic target in cow's milk allergic children suffering from ASD-like symptoms.

So am I correct this relates to small children right? Not implicating onset of neorological Symptons of an autistic nature in adults? BUT suggestive of a negative immune response in general with regards to neurological disorders?

http://www.ncbi.nlm.nih.gov/pubmed/12639817
What about this study?
I didn't completely understAnd it but it seemed pro immune benefits?

Sorry theses studies go over my head Abit.

but with regard to glutamine , turns to arginine which elevates growth hormones etc but is this with ISOLATED supplementation ? In the form of complete protein power does it still have the same effect with HGH?" Therefore short duration use of protein powders?"
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