[sweetorange]

I know the feeling, Ella =(

[sweetorange]

I just re-read your last two posts again Lotus " alt="" title="">  So good to know doing exercise before pumping/massaging is a good idea, too!

For whoever that may want to know her/his heart rate. You have to calculate it with this scheme: 220 - ___ (your age). This would be your maximum heart rate. My case: 193 max, since I am 27 years old.

Then, it's also pretty important to notice at which heart-rate level you may want to workout: super light, light, moderate or hard-at its maximum. I always do light-moderate and the last couple of mins hard, when I do cardio. In lifting terms, I do moderate always but this is just my preference, too. These scales are very easy to notice: light is when you feel you can breathe and talk while you workout; moderate is when you can still talk, but breathing is a bit harder; and hard is when you are sweating a lot hahaha. Watch out these intensities, since they're very helpful to stay healthy and seems good for NBE, too ^^

My example, as well:

Light scale heart-rate: 116 to 135

Moderate:135 to 154

Hard: 154 to 193 (depends a lot on which exercise you do to reach this stage)

 

[Lotus]

Hi Ella, 

Re fenugreek do we add it to aloe Vera for breast massage? 

I don't recommend combining fenugreek with aloe vera for massage, simply for the reason of derivatives. Meaning aloe vera has more benefits than fenugreek, so it'll muck up the benefits of aloe vera. 

Of the two versions of aloe to take, the one with aloin stripped out is easier on the gut. So, when sourcing aloe pick a brand that indicates latex free, which is free of aloin. 

I understand you said it’s not in your protocol but for us you think useful or not? (As you know I can’t do fenugreek internally) .

Fenugreek benefits happen from a liver activation. Finding the molecular weight of fenugreek is all over the place, you'll see the derivatives of fenugreek broken down but not the whole of fenugreek...very strange. But, if one is taking fenugreek for milk supply, moringa will do the same same thing @increasing milk supply. I do remember you can't take fenugreek orally, was defo scary what happened to you. If anyone has low blood sugars please stay away from using fenugreek, it's too risky...it can bottom out blood glucose real fast, and thus you'll pass out (as what happened to Ella). 

Next big question massage with aloe x 1 or twice daily ? I have an organic aloe with as little additives possible. I have an aloe plant but I’d never use that on the bosom. Too much room for contamination around the nipple from dirt. Bacteria etc. 

Ps that’s great you’ve found help with your thyroid.

1x massage per day is sufficient...it only takes about 15min.

Organic is by far a better option IMHO, researchers found organic lowers pesticides residues by 30%. Soy and coffee are two of the most heavily sprayed crops in the world. 

After 25 years of low thyroid issues it's now reversed to normal range, yay. 

[Lotus]

Then this means, orally or topically, aloe vera is a good NBE supplement, right?

Yes, I believe so.

 I put aloe on my skin just in summer season nowadays; in my case i feel too sticky after using it but now you've mentioned it is all good for boobie growth! 

Try adding the olive oil, the two (in my opinion) are synergistic and dries in about 15min, both are of low molecular weight for fast skin metabolism.

[Lotus]

I just re-read your last two posts again Lotus " alt="" title="">  So good to know doing exercise before pumping/massaging is a good idea, too!

For whoever that may want to know her/his heart rate. You have to calculate it with this scheme: 220 - ___ (your age). This would be your maximum heart rate. My case: 193 max, since I am 27 years old.

Then, it's also pretty important to notice at which heart-rate level you may want to workout: super light, light, moderate or hard-at its maximum. I always do light-moderate and the last couple of mins hard, when I do cardio. In lifting terms, I do moderate always but this is just my preference, too. These scales are very easy to notice: light is when you feel you can breathe and talk while you workout; moderate is when you can still talk, but breathing is a bit harder; and hard is when you are sweating a lot hahaha. Watch out these intensities, since they're very helpful to stay healthy and seems good for NBE, too ^^

My example, as well:

Light scale heart-rate: 116 to 135

Moderate:135 to 154

Hard: 154 to 193 (depends a lot on which exercise you do to reach this stage)

 

Great tips sweetorange, thanks for sharing.

[Lotus]

Somatostatin inhibits oral estradiol, prolactin, growth hormone and stomach gastrin  Somatostatin also stimulates insulin, which has deleterious effects to breast growth. So, the new goal needs to inhibit somatostatin. Somatostatin also inhibits the cAMP/PKA/CREB pathway...which is the breast growth pathway. 

Bringing this into focus. A few years ago I posted some information (shared below) regarding cimetidine and how it inhibits stomach gastrin and thereby increases estradiol. Cimetidine and H2 inhibitors aren't the only game in town that inhibits gastrin. Forskolin and aloe vera and some other agents inhibit gastrin. Explaining what somatostatin does is explained in the link below. Trust me when I say somatostatin is about as bad for breast growth as DHT. In closing, inhibiting somatostatin seems to up our game for promoting breast growth. One final note about forskolin, it improves thyroid function, so much so in my case it reversed my hashimoto's of 15 years.

Men have more stomach acid than women, which is why they can produce a bigger pool uptake of estrogen. But if women relax stomach gastrin (or inhibit it) a larger amount of E2 is synthesized in gastric parietal cells.


Estrogen relaxes gastric muscle cells via a nitric oxide‑ and cyclic guanosine monophosphate‑dependent mechanism: A sex‑associated differential effect

In conclusion, estrogen relaxes GSMCs via an NO/cGMP‑dependent mechanism, and the reduced contraction in GSMCs from females by estrogen may be associated with the sex‑associated increased expression of ERα and ERβ, and greater production of NO and cGMP, compared with that in GSMCs from males.
https://www.spandidos-publications.com/etm/16/3/1685


Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion

Ueyama et al. reported that E2 levels in the portal vein were much higher than those in arterial blood, and that the main estrogen was determined as E2 with gas chromatography [18]. They also showed the presence of estrogen synthetase, aromatase or cytochrome P450arom in gastric parietal cells. Gastric E2 is synthesized from progesterone via androstenedione and testosterone by enzyme reactions of 17α-hydroxylase (EC: 4.1.2.30), 17β-hydroxysteroid dehydrogenase type 3 (EC: 1.1.1.62) and aromatase (EC: 1.14.14.1), respectively [19]. Thus, a relatively large amount of E2 is synthesized in gastric parietal cells.

https://www.ncbi.nlm.nih.gov/pmc/article...po=10.7143



Somatostatin 
http://www.vivo.colostate.edu/hbooks/pat...tatin.html

Using H2 Blockers (H2-receptor antagonists) and to a lesser extent H1 receptors antagonists block stomach acid (aka. gastrin) increase plasma estradiol and prolactin.  Drugs like cimetidine and ranitidine (others too) inhibit stomach acid, though ranitidine to a lesser extent nukes the cytochrome (CYP) P450 enzymes. Cimetidine is for a short time (I believe 2-4weeks) to treat stomach acid. If you have normal stomach acid cimetidine and the like aren't necessary, as always consult a health professional.

https://www.breastnexum.com/showthread.php?tid=17436&pid=196127&highlight=cimetidine#pid196127
Post # 3990..

This study demonstrates that the administration of cimetidine to men decreases the 2-hydroxylation of estradiol and results in an increase in the serum estradiol concentration.

The Effects of Cimetidine on the Oxidative Metabolism of Estradiol
https://www.researchgate.net/publication..._Estradiol

[EllaC]

Somatostatin inhibits oral estradiol, prolactin, growth hormone and stomach gastrin  Somatostatin also stimulates insulin, which has deleterious effects to breast growth. So, the new goal needs to inhibit somatostatin. Somatostatin also inhibits the cAMP/PKA/CREB pathway...which is the breast growth pathway. 

Bringing this into focus. A few years ago I posted some information (shared below) regarding cimetidine and how it inhibits stomach gastrin and thereby increases estradiol. Cimetidine and H2 inhibitors aren't the only game in town that inhibits gastrin. Forskolin and aloe vera and some other agents inhibit gastrin. Explaining what somatostatin does is explained in the link below. Trust me when I say somatostatin is about as bad for breast growth as DHT. In closing, inhibiting somatostatin seems to up our game for promoting breast growth. One final note about forskolin, it improves thyroid function, so much so in my case it reversed my hashimoto's of 15 years.

Men have more stomach acid than women, which is why they can produce a bigger pool uptake of estrogen. But if women relax stomach gastrin (or inhibit it) a larger amount of E2 is synthesized in gastric parietal cells.


Estrogen relaxes gastric muscle cells via a nitric oxide‑ and cyclic guanosine monophosphate‑dependent mechanism: A sex‑associated differential effect

In conclusion, estrogen relaxes GSMCs via an NO/cGMP‑dependent mechanism, and the reduced contraction in GSMCs from females by estrogen may be associated with the sex‑associated increased expression of ERα and ERβ, and greater production of NO and cGMP, compared with that in GSMCs from males.
https://www.spandidos-publications.com/etm/16/3/1685


Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion

Ueyama et al. reported that E2 levels in the portal vein were much higher than those in arterial blood, and that the main estrogen was determined as E2 with gas chromatography [18]. They also showed the presence of estrogen synthetase, aromatase or cytochrome P450arom in gastric parietal cells. Gastric E2 is synthesized from progesterone via androstenedione and testosterone by enzyme reactions of 17α-hydroxylase (EC: 4.1.2.30), 17β-hydroxysteroid dehydrogenase type 3 (EC: 1.1.1.62) and aromatase (EC: 1.14.14.1), respectively [19]. Thus, a relatively large amount of E2 is synthesized in gastric parietal cells.

https://www.ncbi.nlm.nih.gov/pmc/article...po=10.7143



Somatostatin 
http://www.vivo.colostate.edu/hbooks/pat...tatin.html

Using H2 Blockers (H2-receptor antagonists) and to a lesser extent H1 receptors antagonists block stomach acid (aka. gastrin) increase plasma estradiol and prolactin.  Drugs like cimetidine and ranitidine (others too) inhibit stomach acid, though ranitidine to a lesser extent nukes the cytochrome (CYP) P450 enzymes. Cimetidine is for a short time (I believe 2-4weeks) to treat stomach acid. If you have normal stomach acid cimetidine and the like aren't necessary, as always consult a health professional.

https://www.breastnexum.com/showthread.php?tid=17436&pid=196127&highlight=cimetidine#pid196127
Post # 3990..

This study demonstrates that the administration of cimetidine to men decreases the 2-hydroxylation of estradiol and results in an increase in the serum estradiol concentration.

The Effects of Cimetidine on the Oxidative Metabolism of Estradiol
https://www.researchgate.net/publication..._Estradiol

In English xxxx how do we replicate in layman’s terms  xxx. (Love ya!!)

[sweetorange]

Lotus, can vitex be good for breast growth??

Not sure if I am taking it properly for balancing out my hormones. I understood I have to take it only in follicular phase.

[sweetorange]

Forgot to give a bit of background xD. Let's see if you guys can help me!

I have all my Ts out of balance. Testosterone and free T are just +1 away of normal standards, but DHT ...ha, that's another story. It's high indeed, around 300 and I am a cis-female.  So yes, my only concern is hirsutism.

I contacted a naturopath doctor and she ruled out PCOS since my FHS levels are normal, and insulin too. My periods are really on time always, so she suggested it may be Adrenal PCOS - due to my anxiety, stress and so on - and prescribed me Zinc+ Dim and Saw Palmetto at first. But SP gave me nausea and switched it to Vitex.

I know taking Zinc daily won't harm my cycle, but I have my doubts with DIM and Vitex. I take DIM after my period is gone and I am not having issues yet with it but I am not sure if I am taking it correctly (Dr said all month but...).

Now, I know Vitex cannot be taken everyday and I looked it up and seems just for follicular phase. But my periods are pretty regular, so I have no idea what to think since Vitex is adaptogen, right?

Also, I used to take reishi in liquid form and I don't know if I should keep using it.

So I just want to balance out my hormones and see if I can get some benefit too for NBE from this haha, even though is hard and a long-term process.

[hannah]

I am starting to understand it Lotus, I might need another read lol. But is fenugreek a no-go now? Because i started taking it internally mid cycle according Dynselli's e-book. And it does what is says for me. I am combining it with soy and spearmint but thats another story. Also have about a kilo of that stuff atm   I am not going to throw that all away lol.

So one question what is more effective internal aloe vera or external application? And should I get it fresh from a plant?
And is it either the lavender oil or either the aloe vera since both are phytoestrogenic or can we combine both?

Massaging aloe plus olive oil didnt had a lot of effect on me in the past...but its worth another try!
There are times in nbe where you react to things and times when it just doesnt work. I know it is some kinda receptor thing.